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Zinc finger CCCH-type antiviral protein 1

Intramolecular
Cysteine 78 and cysteine 82 L
Cysteine 73 and cysteine 78 L
Cysteine 182 and cysteine 187
Cysteine 150 and cysteine 162
Cysteine 521 and cysteine 527
Cysteine 162 and cysteine 168
Cysteine 150 and cysteine 168
Cysteine 88 and cysteine 96 L
Cysteine 96 and cysteine 106
Cysteine 513 and cysteine 521
More...
Cysteine 174 and cysteine 187
Cysteine 73 and cysteine 82 L
Cysteine 513 and cysteine 527
Cysteine 174 and cysteine 182
Cysteine 88 and cysteine 106 L
Cysteine 15 and cysteine 136 L
Cysteine 567 and cysteine 581
Cysteine 7 and cysteine 8
Cysteine 8 and cysteine 15 L
Cysteine 174 and cysteine 219
A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 78 and 82.

Details

Redox score ?
93
PDB code
6uei
Structure name
crystal structure of human zinc finger antiviral protein
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
35
Minimum pKa ?
5
% buried
2
Peptide accession
Q7Z2W4
Residue number A
78
Residue number B
82
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 78 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 82 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 73 and 78.

Details

Redox score ?
91
PDB code
6uei
Structure name
crystal structure of human zinc finger antiviral protein
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
5
% buried
8
Peptide accession
Q7Z2W4
Residue number A
73
Residue number B
78
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 73 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 78 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 182 and 187.

Details

Redox score ?
88
PDB code
6uej
Structure name
crystal structure of human zinc finger antiviral protein bound to rna
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
7
% buried
13
Peptide accession
Q7Z2W4
Residue number A
182
Residue number B
187
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 182 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 187 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 150 and 162.

Details

Redox score ?
87
PDB code
6uei
Structure name
crystal structure of human zinc finger antiviral protein
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
6
% buried
0
Peptide accession
Q7Z2W4
Residue number A
150
Residue number B
162
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 150 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 162 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 521 and 527.

Details

Redox score ?
87
PDB code
7kzh
Structure name
zinc finger antiviral protein (zap) central domain
Structure deposition date
2020-12-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
8
% buried
0
Peptide accession
Q7Z2W4
Residue number A
521
Residue number B
527
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 521 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 527 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 162 and 168.

Details

Redox score ?
86
PDB code
6uej
Structure name
crystal structure of human zinc finger antiviral protein bound to rna
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
8
% buried
0
Peptide accession
Q7Z2W4
Residue number A
162
Residue number B
168
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 162 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 168 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 150 and 168.

Details

Redox score ?
85
PDB code
6l1w
Structure name
zinc-finger antiviral protein (zap) bound to rna
Structure deposition date
2019-09-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
6
% buried
28
Peptide accession
Q3UPF5
Residue number A
150
Residue number B
168
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 150 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 168 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 88 and 96.

Details

Redox score ?
85
PDB code
6uej
Structure name
crystal structure of human zinc finger antiviral protein bound to rna
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
7
% buried
29
Peptide accession
Q7Z2W4
Residue number A
88
Residue number B
96
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 88 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 96 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 96 and 106.

Details

Redox score ?
84
PDB code
6l1w
Structure name
zinc-finger antiviral protein (zap) bound to rna
Structure deposition date
2019-09-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
8
% buried
28
Peptide accession
Q3UPF5
Residue number A
96
Residue number B
106
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 96 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 106 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 513 and 521.

Details

Redox score ?
83
PDB code
7kzh
Structure name
zinc finger antiviral protein (zap) central domain
Structure deposition date
2020-12-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
7
% buried
4
Peptide accession
Q7Z2W4
Residue number A
513
Residue number B
521
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 513 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 521 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 174 and 187.

Details

Redox score ?
83
PDB code
6uej
Structure name
crystal structure of human zinc finger antiviral protein bound to rna
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
7
% buried
27
Peptide accession
Q7Z2W4
Residue number A
174
Residue number B
187
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 174 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 187 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 73 and 82.

Details

Redox score ?
82
PDB code
6uei
Structure name
crystal structure of human zinc finger antiviral protein
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
8
% buried
10
Peptide accession
Q7Z2W4
Residue number A
73
Residue number B
82
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 73 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 82 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 513 and 527.

Details

Redox score ?
82
PDB code
7tgq
Structure name
zinc finger antiviral protein (zap) central domain bound to adp-ribose
Structure deposition date
2022-01-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
7
% buried
4
Peptide accession
Q7Z2W4
Residue number A
513
Residue number B
527
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 513 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 527 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 174 and 182.

Details

Redox score ?
79
PDB code
6uei
Structure name
crystal structure of human zinc finger antiviral protein
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
9
% buried
20
Peptide accession
Q7Z2W4
Residue number A
174
Residue number B
182
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 174 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 182 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 88 and 106.

Details

Redox score ?
78
PDB code
6uej
Structure name
crystal structure of human zinc finger antiviral protein bound to rna
Structure deposition date
2019-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
36
Peptide accession
Q7Z2W4
Residue number A
88
Residue number B
106
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 88 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 106 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 15 and 136. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
60
PDB code
3u9g
Structure name
crystal structure of the zinc finger antiviral protein
Structure deposition date
2011-10-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
74
Minimum pKa ?
11
% buried
74
Peptide accession
Q8K3Y6
Residue number A
15
Residue number B
136
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 15 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 136 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 567 and 581. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
49
PDB code
7tgq
Structure name
zinc finger antiviral protein (zap) central domain bound to adp-ribose
Structure deposition date
2022-01-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
57
Minimum pKa ?
10
% buried
26
Peptide accession
Q7Z2W4
Residue number A
567
Residue number B
581
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 567 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 581 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 7 and 8. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
6uej
Structure name
crystal structure of human zinc finger antiviral protein bound to rna
Structure deposition date
2019-09-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
9
% buried
38
Peptide accession
Q7Z2W4
Residue number A
7
Residue number B
8
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 7 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 8 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 8 and 15. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
6uej
Structure name
crystal structure of human zinc finger antiviral protein bound to rna
Structure deposition date
2019-09-21
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
64
Peptide accession
Q7Z2W4
Residue number A
8
Residue number B
15
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 8 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 15 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger CCCH-type antiviral protein 1 between cysteines 174 and 219. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
34
PDB code
6uei
Structure name
crystal structure of human zinc finger antiviral protein
Structure deposition date
2019-09-21
Thiol separation (Å)
10
Half-sphere exposure sum ?
66
Minimum pKa ?
11
% buried
64
Peptide accession
Q7Z2W4
Residue number A
174
Residue number B
219
Peptide name
Zinc finger CCCH-type antiviral protein 1

Ligandability

Cysteine 174 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 219 of Zinc finger CCCH-type antiviral protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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