Elongation factor-like GTPase 1
Intermolecular
Cysteine 210 of Ribosome maturation protein SBDS and cysteine 934
Intramolecular
Cysteine 23 and cysteine 110
Cysteine 599 and cysteine 604 L
Cysteine 110 and cysteine 113
Cysteine 646 and cysteine 670
Cysteine 23 and cysteine 113
Cysteine 38 and cysteine 345
5anb J 210 K 934
A redox-regulated disulphide may form between cysteine 210 of Ribosome maturation protein SBDS and cysteine 934 of Elongation factor-like GTPase 1. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5anb
Structure name
mechanism of eif6 release from the nascent 60s ribosomal subunit
Structure deposition date
2015-09-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
73
Minimum pKa ?
11
% buried
90
Peptide A name
Ribosome maturation protein SBDS
Peptide B name
Elongation factor-like GTPase 1
Peptide A accession
Q9Y3A5
Peptide B accession
Q7Z2Z2
Peptide A residue number
210
Peptide B residue number
934
Ligandability
Cysteine 210 of Ribosome maturation protein SBDS
Cysteine 934 of Elongation factor-like GTPase 1
5anb K 23 K 110
A redox-regulated disulphide may form within Elongation factor-like GTPase 1 between cysteines 23 and 110.
Details
Redox score ?
71
PDB code
5anb
Structure name
mechanism of eif6 release from the nascent 60s ribosomal subunit
Structure deposition date
2015-09-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
93
Minimum pKa ?
8
% buried
100
Peptide accession
Q7Z2Z2
Residue number A
23
Residue number B
110
Peptide name
Elongation factor-like GTPase 1
Ligandability
Cysteine 23 of Elongation factor-like GTPase 1
Cysteine 110 of Elongation factor-like GTPase 1
5anc K 599 K 604
A redox-regulated disulphide may form within Elongation factor-like GTPase 1 between cysteines 599 and 604.
Details
Redox score ?
70
PDB code
5anc
Structure name
mechanism of eif6 release from the nascent 60s ribosomal subunit
Structure deposition date
2015-09-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
8
% buried
98
Peptide accession
Q7Z2Z2
Residue number A
599
Residue number B
604
Peptide name
Elongation factor-like GTPase 1
Ligandability
Cysteine 599 of Elongation factor-like GTPase 1
Cysteine 604 of Elongation factor-like GTPase 1
5anc K 110 K 113
A redox-regulated disulphide may form within Elongation factor-like GTPase 1 between cysteines 110 and 113. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
5anc
Structure name
mechanism of eif6 release from the nascent 60s ribosomal subunit
Structure deposition date
2015-09-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
92
Minimum pKa ?
7
% buried
100
Peptide accession
Q7Z2Z2
Residue number A
110
Residue number B
113
Peptide name
Elongation factor-like GTPase 1
Ligandability
Cysteine 110 of Elongation factor-like GTPase 1
Cysteine 113 of Elongation factor-like GTPase 1
5anc K 646 K 670
A redox-regulated disulphide may form within Elongation factor-like GTPase 1 between cysteines 646 and 670. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
5anc
Structure name
mechanism of eif6 release from the nascent 60s ribosomal subunit
Structure deposition date
2015-09-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
82
Minimum pKa ?
12
% buried
100
Peptide accession
Q7Z2Z2
Residue number A
646
Residue number B
670
Peptide name
Elongation factor-like GTPase 1
Ligandability
Cysteine 646 of Elongation factor-like GTPase 1
Cysteine 670 of Elongation factor-like GTPase 1
5anc K 23 K 113
A redox-regulated disulphide may form within Elongation factor-like GTPase 1 between cysteines 23 and 113. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
5anc
Structure name
mechanism of eif6 release from the nascent 60s ribosomal subunit
Structure deposition date
2015-09-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
85
Minimum pKa ?
12
% buried
100
Peptide accession
Q7Z2Z2
Residue number A
23
Residue number B
113
Peptide name
Elongation factor-like GTPase 1
Ligandability
Cysteine 23 of Elongation factor-like GTPase 1
Cysteine 113 of Elongation factor-like GTPase 1
5anb K 38 K 345
A redox-regulated disulphide may form within Elongation factor-like GTPase 1 between cysteines 38 and 345. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
29
PDB code
5anb
Structure name
mechanism of eif6 release from the nascent 60s ribosomal subunit
Structure deposition date
2015-09-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
77
Minimum pKa ?
12
% buried
89
Peptide accession
Q7Z2Z2
Residue number A
38
Residue number B
345
Peptide name
Elongation factor-like GTPase 1
Ligandability
Cysteine 38 of Elongation factor-like GTPase 1
Cysteine 345 of Elongation factor-like GTPase 1
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