LIM and senescent cell antigen-like-containing domain protein 2
Intramolecular
Cysteine 43 and cysteine 64
Cysteine 15 and cysteine 18
Cysteine 15 and cysteine 40
Cysteine 46 and cysteine 64
Cysteine 18 and cysteine 40
Cysteine 43 and cysteine 46
3ixe B 38 B 59
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 2 between cysteines 43 and 64 (38 and 59 respectively in this structure).
Details
Redox score ?
86
PDB code
3ixe
Structure name
structural basis of competition between pinch1 and pinch2 for binding to the ankyrin repeat domain of integrin-linked kinase
Structure deposition date
2009-09-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
3
% buried
72
Peptide accession
Q7Z4I7
Residue number A
43
Residue number B
64
Peptide name
LIM and senescent cell antigen-like-containing domain protein 2
Ligandability
Cysteine 43 of LIM and senescent cell antigen-like-containing domain protein 2
Cysteine 64 of LIM and senescent cell antigen-like-containing domain protein 2
3ixe B 10 B 13
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 2 between cysteines 15 and 18 (10 and 13 respectively in this structure).
Details
Redox score ?
86
PDB code
3ixe
Structure name
structural basis of competition between pinch1 and pinch2 for binding to the ankyrin repeat domain of integrin-linked kinase
Structure deposition date
2009-09-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
5
% buried
42
Peptide accession
Q7Z4I7
Residue number A
15
Residue number B
18
Peptide name
LIM and senescent cell antigen-like-containing domain protein 2
Ligandability
Cysteine 15 of LIM and senescent cell antigen-like-containing domain protein 2
Cysteine 18 of LIM and senescent cell antigen-like-containing domain protein 2
3ixe B 10 B 35
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 2 between cysteines 15 and 40 (10 and 35 respectively in this structure).
Details
Redox score ?
83
PDB code
3ixe
Structure name
structural basis of competition between pinch1 and pinch2 for binding to the ankyrin repeat domain of integrin-linked kinase
Structure deposition date
2009-09-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
5
% buried
56
Peptide accession
Q7Z4I7
Residue number A
15
Residue number B
40
Peptide name
LIM and senescent cell antigen-like-containing domain protein 2
Ligandability
Cysteine 15 of LIM and senescent cell antigen-like-containing domain protein 2
Cysteine 40 of LIM and senescent cell antigen-like-containing domain protein 2
3ixe B 41 B 59
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 2 between cysteines 46 and 64 (41 and 59 respectively in this structure).
Details
Redox score ?
83
PDB code
3ixe
Structure name
structural basis of competition between pinch1 and pinch2 for binding to the ankyrin repeat domain of integrin-linked kinase
Structure deposition date
2009-09-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
3
% buried
66
Peptide accession
Q7Z4I7
Residue number A
46
Residue number B
64
Peptide name
LIM and senescent cell antigen-like-containing domain protein 2
Ligandability
Cysteine 46 of LIM and senescent cell antigen-like-containing domain protein 2
Cysteine 64 of LIM and senescent cell antigen-like-containing domain protein 2
3ixe B 13 B 35
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 2 between cysteines 18 and 40 (13 and 35 respectively in this structure).
Details
Redox score ?
73
PDB code
3ixe
Structure name
structural basis of competition between pinch1 and pinch2 for binding to the ankyrin repeat domain of integrin-linked kinase
Structure deposition date
2009-09-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
10
% buried
56
Peptide accession
Q7Z4I7
Residue number A
18
Residue number B
40
Peptide name
LIM and senescent cell antigen-like-containing domain protein 2
Ligandability
Cysteine 18 of LIM and senescent cell antigen-like-containing domain protein 2
Cysteine 40 of LIM and senescent cell antigen-like-containing domain protein 2
3ixe B 38 B 41
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 2 between cysteines 43 and 46 (38 and 41 respectively in this structure).
Details
Redox score ?
69
PDB code
3ixe
Structure name
structural basis of competition between pinch1 and pinch2 for binding to the ankyrin repeat domain of integrin-linked kinase
Structure deposition date
2009-09-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
86
Peptide accession
Q7Z4I7
Residue number A
43
Residue number B
46
Peptide name
LIM and senescent cell antigen-like-containing domain protein 2
Ligandability
Cysteine 43 of LIM and senescent cell antigen-like-containing domain protein 2
Cysteine 46 of LIM and senescent cell antigen-like-containing domain protein 2
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