ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Protein prenyltransferase alpha subunit repeat-containing protein 1

Intramolecular
Cysteine 37 and cysteine 60
A redox-regulated disulphide may form within Protein prenyltransferase alpha subunit repeat-containing protein 1 between cysteines 37 and 60. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
6j7x
Structure name
complex of ggtaseiii, farnesyl-ykt6, and ggpp
Structure deposition date
2019-01-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
10
% buried
48
Peptide accession
Q7Z6K3
Residue number A
37
Residue number B
60
Peptide name
Protein prenyltransferase alpha subunit repeat-containing protein 1

Ligandability

Cysteine 37 of Protein prenyltransferase alpha subunit repeat-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 60 of Protein prenyltransferase alpha subunit repeat-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: