ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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V-set domain-containing T-cell activation inhibitor 1

Intramolecular
Cysteine 56 and cysteine 130
A redox-regulated disulphide may form within V-set domain-containing T-cell activation inhibitor 1 between cysteines 56 and 130.

Details

Redox score ?
82
PDB code
4gos
Structure name
crystal structure of human b7-h4 igv-like domain
Structure deposition date
2012-08-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q7Z7D3
Residue number A
56
Residue number B
130
Peptide name
V-set domain-containing T-cell activation inhibitor 1

Ligandability

Cysteine 56 of V-set domain-containing T-cell activation inhibitor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 130 of V-set domain-containing T-cell activation inhibitor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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