ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Zinc finger and SCAN domain-containing protein 2

Intramolecular
Cysteine 588 and cysteine 255
Cysteine 336 and cysteine 255
A redox-regulated disulphide may form within Zinc finger and SCAN domain-containing protein 2 between cysteines 588 and 255 (136 and 139 respectively in this structure).

Details

Redox score ?
91
PDB code
2i13
Structure name
aart, a six finger zinc finger designed to recognize ann triplets
Structure deposition date
2006-08-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
38
Minimum pKa ?
5
% buried
0
Peptide accession
Q07230
Residue number A
588
Residue number B
255
Peptide name
Zinc finger and SCAN domain-containing protein 2

Ligandability

Cysteine 588 of Zinc finger and SCAN domain-containing protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 255 of Zinc finger and SCAN domain-containing protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger and SCAN domain-containing protein 2 between cysteines 336 and 255 (108 and 111 respectively in this structure).

Details

Redox score ?
87
PDB code
2i13
Structure name
aart, a six finger zinc finger designed to recognize ann triplets
Structure deposition date
2006-08-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
6
% buried
16
Peptide accession
Q07230
Residue number A
336
Residue number B
255
Peptide name
Zinc finger and SCAN domain-containing protein 2

Ligandability

Cysteine 336 of Zinc finger and SCAN domain-containing protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 255 of Zinc finger and SCAN domain-containing protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: