Polycomb group RING finger protein 5
Intramolecular
Cysteine 53 and cysteine 56
Cysteine 34 and cysteine 53
Cysteine 18 and cysteine 21
Cysteine 21 and cysteine 39
Cysteine 21 and cysteine 42
Cysteine 34 and cysteine 56
Cysteine 18 and cysteine 39
Cysteine 39 and cysteine 42
Cysteine 18 and cysteine 42
4s3o F 53 F 56
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 53 and 56.
Details
Redox score ?
90
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
2
% buried
28
Peptide accession
Q86SE9
Residue number A
53
Residue number B
56
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 53 of Polycomb group RING finger protein 5
Cysteine 56 of Polycomb group RING finger protein 5
4s3o C 34 C 53
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 34 and 53.
Details
Redox score ?
88
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
2
% buried
46
Peptide accession
Q86SE9
Residue number A
34
Residue number B
53
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 34 of Polycomb group RING finger protein 5
Cysteine 53 of Polycomb group RING finger protein 5
4s3o C 18 C 21
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 18 and 21.
Details
Redox score ?
84
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
5
% buried
nan
Peptide accession
Q86SE9
Residue number A
18
Residue number B
21
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 18 of Polycomb group RING finger protein 5
Cysteine 21 of Polycomb group RING finger protein 5
4s3o C 21 C 39
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 21 and 39.
Details
Redox score ?
80
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
5
% buried
72
Peptide accession
Q86SE9
Residue number A
21
Residue number B
39
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 21 of Polycomb group RING finger protein 5
Cysteine 39 of Polycomb group RING finger protein 5
4s3o F 21 F 42
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 21 and 42.
Details
Redox score ?
80
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
5
% buried
53
Peptide accession
Q86SE9
Residue number A
21
Residue number B
42
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 21 of Polycomb group RING finger protein 5
Cysteine 42 of Polycomb group RING finger protein 5
4s3o C 34 C 56
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 34 and 56.
Details
Redox score ?
76
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
8
% buried
27
Peptide accession
Q86SE9
Residue number A
34
Residue number B
56
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 34 of Polycomb group RING finger protein 5
Cysteine 56 of Polycomb group RING finger protein 5
4s3o C 18 C 39
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 18 and 39.
Details
Redox score ?
64
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
13
% buried
nan
Peptide accession
Q86SE9
Residue number A
18
Residue number B
39
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 18 of Polycomb group RING finger protein 5
Cysteine 39 of Polycomb group RING finger protein 5
4s3o F 39 F 42
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 39 and 42. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
13
% buried
76
Peptide accession
Q86SE9
Residue number A
39
Residue number B
42
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 39 of Polycomb group RING finger protein 5
Cysteine 42 of Polycomb group RING finger protein 5
4s3o F 18 F 42
A redox-regulated disulphide may form within Polycomb group RING finger protein 5 between cysteines 18 and 42. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
4s3o
Structure name
pcgf5-ring1b-ubch5c complex
Structure deposition date
2015-03-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
70
Minimum pKa ?
22
% buried
nan
Peptide accession
Q86SE9
Residue number A
18
Residue number B
42
Peptide name
Polycomb group RING finger protein 5
Ligandability
Cysteine 18 of Polycomb group RING finger protein 5
Cysteine 42 of Polycomb group RING finger protein 5
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