a tool for identifying drug-targetable redox-active disulphides

Protein S100-A7A

Intramolecular

Cysteine 47 and cysteine 96

A redox-regulated disulphide may form within Protein S100-A7A between cysteines 47 and 96 (46 and 95 respectively in this structure).

Details

Redox score ?

86

PDB code

Structure name

structure of human s100a15 bound to zinc and calcium

Structure deposition date

2012-04-17

Thiol separation (Å)

2

Half-sphere exposure sum ?

49

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

47

Residue number B

96

Peptide name

Protein S100-A7A

Ligandability

Cysteine 47 of Protein S100-A7A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 96 of Protein S100-A7A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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