Glutaredoxin-related protein 5, mitochondrial

Intermolecular

Intramolecular

A redox-regulated disulphide may form between two units of Glutaredoxin-related protein 5, mitochondrial at cysteines 67 and 67. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2wul

Structure name

crystal structure of the human glutaredoxin 5 with bound glutathione in an fes cluster

Structure deposition date

2009-10-06

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Glutaredoxin-related protein 5, mitochondrial

Peptide B name

Glutaredoxin-related protein 5, mitochondrial

Peptide A accession

Q86SX6

Peptide B accession

Q86SX6

Peptide A residue number

Peptide B residue number

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Glutaredoxin-related protein 5, mitochondrial between cysteines 67 and 122. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?