Low-density lipoprotein receptor class A domain-containing protein 3
Intramolecular
Cysteine 49 and cysteine 64
Cysteine 29 and cysteine 42
Cysteine 37 and cysteine 42
Cysteine 29 and cysteine 37
Cysteine 42 and cysteine 55
Cysteine 29 and cysteine 55
7ffn M 49 M 64
A redox-regulated disulphide may form within Low-density lipoprotein receptor class A domain-containing protein 3 between cysteines 49 and 64.
Details
Redox score ?
88
PDB code
7ffn
Structure name
cryo-em structure of veev vlp-ldlrad3-d1 complex at the 5-fold axes
Structure deposition date
2021-07-23
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q86YD5
Residue number A
49
Residue number B
64
Peptide name
Low-density lipoprotein receptor class A domain-containing protein 3
Ligandability
Cysteine 49 of Low-density lipoprotein receptor class A domain-containing protein 3
Cysteine 64 of Low-density lipoprotein receptor class A domain-containing protein 3
7ffn M 29 M 42
A redox-regulated disulphide may form within Low-density lipoprotein receptor class A domain-containing protein 3 between cysteines 29 and 42.
Details
Redox score ?
86
PDB code
7ffn
Structure name
cryo-em structure of veev vlp-ldlrad3-d1 complex at the 5-fold axes
Structure deposition date
2021-07-23
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q86YD5
Residue number A
29
Residue number B
42
Peptide name
Low-density lipoprotein receptor class A domain-containing protein 3
Ligandability
Cysteine 29 of Low-density lipoprotein receptor class A domain-containing protein 3
Cysteine 42 of Low-density lipoprotein receptor class A domain-containing protein 3
7ffn M 37 M 42
A redox-regulated disulphide may form within Low-density lipoprotein receptor class A domain-containing protein 3 between cysteines 37 and 42. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
7ffn
Structure name
cryo-em structure of veev vlp-ldlrad3-d1 complex at the 5-fold axes
Structure deposition date
2021-07-23
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q86YD5
Residue number A
37
Residue number B
42
Peptide name
Low-density lipoprotein receptor class A domain-containing protein 3
Ligandability
Cysteine 37 of Low-density lipoprotein receptor class A domain-containing protein 3
Cysteine 42 of Low-density lipoprotein receptor class A domain-containing protein 3
7ffn M 29 M 37
A redox-regulated disulphide may form within Low-density lipoprotein receptor class A domain-containing protein 3 between cysteines 29 and 37. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7ffn
Structure name
cryo-em structure of veev vlp-ldlrad3-d1 complex at the 5-fold axes
Structure deposition date
2021-07-23
Thiol separation (Å)
8
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q86YD5
Residue number A
29
Residue number B
37
Peptide name
Low-density lipoprotein receptor class A domain-containing protein 3
Ligandability
Cysteine 29 of Low-density lipoprotein receptor class A domain-containing protein 3
Cysteine 37 of Low-density lipoprotein receptor class A domain-containing protein 3
7ffn M 42 M 55
A redox-regulated disulphide may form within Low-density lipoprotein receptor class A domain-containing protein 3 between cysteines 42 and 55. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7ffn
Structure name
cryo-em structure of veev vlp-ldlrad3-d1 complex at the 5-fold axes
Structure deposition date
2021-07-23
Thiol separation (Å)
8
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q86YD5
Residue number A
42
Residue number B
55
Peptide name
Low-density lipoprotein receptor class A domain-containing protein 3
Ligandability
Cysteine 42 of Low-density lipoprotein receptor class A domain-containing protein 3
Cysteine 55 of Low-density lipoprotein receptor class A domain-containing protein 3
7ffn M 29 M 55
A redox-regulated disulphide may form within Low-density lipoprotein receptor class A domain-containing protein 3 between cysteines 29 and 55. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
7ffn
Structure name
cryo-em structure of veev vlp-ldlrad3-d1 complex at the 5-fold axes
Structure deposition date
2021-07-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q86YD5
Residue number A
29
Residue number B
55
Peptide name
Low-density lipoprotein receptor class A domain-containing protein 3
Ligandability
Cysteine 29 of Low-density lipoprotein receptor class A domain-containing protein 3
Cysteine 55 of Low-density lipoprotein receptor class A domain-containing protein 3
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