a tool for identifying drug-targetable redox-active disulphides

Beta-klotho

Intramolecular

Cysteine 576 and cysteine 625

A redox-regulated disulphide may form within Beta-klotho between cysteines 576 and 625.

Details

Redox score ?

85

PDB code

Structure name

crystal structure of beta-klotho

Structure deposition date

2017-03-27

Thiol separation (Å)

2

Half-sphere exposure sum ?

56

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

576

Residue number B

625

Peptide name

Beta-klotho

Ligandability

Cysteine 576 of Beta-klotho

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 625 of Beta-klotho

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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