MH1 domain-containing protein
Intramolecular
Cysteine 109 and cysteine 121
Cysteine 64 and cysteine 109
Cysteine 64 and cysteine 121
Cysteine 108 and cysteine 109
Cysteine 108 and cysteine 121
Cysteine 64 and cysteine 108
Cysteine 89 and cysteine 121
Cysteine 89 and cysteine 109
3kmp B 109 B 121
A redox-regulated disulphide may form within MH1 domain-containing protein between cysteines 109 and 121.
Details
Redox score ?
79
PDB code
3kmp
Structure name
crystal structure of smad1-mh1/dna complex
Structure deposition date
2009-11-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
7
% buried
64
Peptide accession
Q8CC31
Residue number A
109
Residue number B
121
Peptide name
MH1 domain-containing protein
Ligandability
Cysteine 109 of MH1 domain-containing protein
Cysteine 121 of MH1 domain-containing protein
3kmp B 64 B 109
A redox-regulated disulphide may form within MH1 domain-containing protein between cysteines 64 and 109.
Details
Redox score ?
79
PDB code
3kmp
Structure name
crystal structure of smad1-mh1/dna complex
Structure deposition date
2009-11-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
9
% buried
43
Peptide accession
Q8CC31
Residue number A
64
Residue number B
109
Peptide name
MH1 domain-containing protein
Ligandability
Cysteine 64 of MH1 domain-containing protein
Cysteine 109 of MH1 domain-containing protein
3kmp B 64 B 121
A redox-regulated disulphide may form within MH1 domain-containing protein between cysteines 64 and 121.
Details
Redox score ?
74
PDB code
3kmp
Structure name
crystal structure of smad1-mh1/dna complex
Structure deposition date
2009-11-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
7
% buried
60
Peptide accession
Q8CC31
Residue number A
64
Residue number B
121
Peptide name
MH1 domain-containing protein
Ligandability
Cysteine 64 of MH1 domain-containing protein
Cysteine 121 of MH1 domain-containing protein
3kmp A 108 A 109
A redox-regulated disulphide may form within MH1 domain-containing protein between cysteines 108 and 109.
Details
Redox score ?
64
PDB code
3kmp
Structure name
crystal structure of smad1-mh1/dna complex
Structure deposition date
2009-11-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
45
Minimum pKa ?
9
% buried
28
Peptide accession
Q8CC31
Residue number A
108
Residue number B
109
Peptide name
MH1 domain-containing protein
Ligandability
Cysteine 108 of MH1 domain-containing protein
Cysteine 109 of MH1 domain-containing protein
3kmp A 108 A 121
A redox-regulated disulphide may form within MH1 domain-containing protein between cysteines 108 and 121. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
60
PDB code
3kmp
Structure name
crystal structure of smad1-mh1/dna complex
Structure deposition date
2009-11-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
58
Minimum pKa ?
3
% buried
44
Peptide accession
Q8CC31
Residue number A
108
Residue number B
121
Peptide name
MH1 domain-containing protein
Ligandability
Cysteine 108 of MH1 domain-containing protein
Cysteine 121 of MH1 domain-containing protein
3kmp B 64 B 108
A redox-regulated disulphide may form within MH1 domain-containing protein between cysteines 64 and 108. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
3kmp
Structure name
crystal structure of smad1-mh1/dna complex
Structure deposition date
2009-11-11
Thiol separation (Å)
7
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
24
Peptide accession
Q8CC31
Residue number A
64
Residue number B
108
Peptide name
MH1 domain-containing protein
Ligandability
Cysteine 64 of MH1 domain-containing protein
Cysteine 108 of MH1 domain-containing protein
3kmp B 89 B 121
A redox-regulated disulphide may form within MH1 domain-containing protein between cysteines 89 and 121. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
3kmp
Structure name
crystal structure of smad1-mh1/dna complex
Structure deposition date
2009-11-11
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
7
% buried
81
Peptide accession
Q8CC31
Residue number A
89
Residue number B
121
Peptide name
MH1 domain-containing protein
Ligandability
Cysteine 89 of MH1 domain-containing protein
Cysteine 121 of MH1 domain-containing protein
3kmp B 89 B 109
A redox-regulated disulphide may form within MH1 domain-containing protein between cysteines 89 and 109. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
3kmp
Structure name
crystal structure of smad1-mh1/dna complex
Structure deposition date
2009-11-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
62
Minimum pKa ?
11
% buried
64
Peptide accession
Q8CC31
Residue number A
89
Residue number B
109
Peptide name
MH1 domain-containing protein
Ligandability
Cysteine 89 of MH1 domain-containing protein
Cysteine 109 of MH1 domain-containing protein
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