Kinase suppressor of Ras 1
Intramolecular
Cysteine 359 and cysteine 377
Cysteine 346 and cysteine 349
Cysteine 346 and cysteine 370
Cysteine 362 and cysteine 377
Cysteine 349 and cysteine 370
Cysteine 346 and cysteine 366
Cysteine 366 and cysteine 377
Cysteine 359 and cysteine 366
Cysteine 83 and cysteine 164
Cysteine 359 and cysteine 362
More...Cysteine 366 and cysteine 370
Cysteine 362 and cysteine 366
Cysteine 349 and cysteine 366
Cysteine 39 and cysteine 83
1kbf A 359 A 377
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 359 and 377.
Details
Redox score ?
87
PDB code
1kbf
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q61097
Residue number A
359
Residue number B
377
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 359 of Kinase suppressor of Ras 1
Cysteine 377 of Kinase suppressor of Ras 1
1kbe A 346 A 349
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 346 and 349.
Details
Redox score ?
85
PDB code
1kbe
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
6
% buried
0
Peptide accession
Q61097
Residue number A
346
Residue number B
349
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 346 of Kinase suppressor of Ras 1
Cysteine 349 of Kinase suppressor of Ras 1
1kbe A 346 A 370
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 346 and 370.
Details
Redox score ?
85
PDB code
1kbe
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
6
% buried
0
Peptide accession
Q61097
Residue number A
346
Residue number B
370
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 346 of Kinase suppressor of Ras 1
Cysteine 370 of Kinase suppressor of Ras 1
1kbe A 362 A 377
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 362 and 377.
Details
Redox score ?
79
PDB code
1kbe
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
3
Half-sphere exposure sum ?
35
Minimum pKa ?
10
% buried
nan
Peptide accession
Q61097
Residue number A
362
Residue number B
377
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 362 of Kinase suppressor of Ras 1
Cysteine 377 of Kinase suppressor of Ras 1
1kbf A 349 A 370
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 349 and 370.
Details
Redox score ?
76
PDB code
1kbf
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
9
% buried
0
Peptide accession
Q61097
Residue number A
349
Residue number B
370
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 349 of Kinase suppressor of Ras 1
Cysteine 370 of Kinase suppressor of Ras 1
1kbe A 346 A 366
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 346 and 366.
Details
Redox score ?
67
PDB code
1kbe
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
63
Minimum pKa ?
6
% buried
8
Peptide accession
Q61097
Residue number A
346
Residue number B
366
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 346 of Kinase suppressor of Ras 1
Cysteine 366 of Kinase suppressor of Ras 1
1kbf A 366 A 377
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 366 and 377. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
1kbf
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
54
Minimum pKa ?
10
% buried
8
Peptide accession
Q61097
Residue number A
366
Residue number B
377
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 366 of Kinase suppressor of Ras 1
Cysteine 377 of Kinase suppressor of Ras 1
1kbe A 359 A 366
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 359 and 366. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
1kbe
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
59
Minimum pKa ?
10
% buried
nan
Peptide accession
Q61097
Residue number A
359
Residue number B
366
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 359 of Kinase suppressor of Ras 1
Cysteine 366 of Kinase suppressor of Ras 1
2lpe A 83 A 164
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 83 and 164. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
2lpe
Structure name
solution nmr structure of the ksr1 ca1-ca1a domain
Structure deposition date
2012-02-11
Thiol separation (Å)
7
Half-sphere exposure sum ?
63
Minimum pKa ?
9
% buried
60
Peptide accession
Q61097
Residue number A
83
Residue number B
164
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 83 of Kinase suppressor of Ras 1
Cysteine 164 of Kinase suppressor of Ras 1
1kbf A 359 A 362
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 359 and 362. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
1kbf
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
24
% buried
0
Peptide accession
Q61097
Residue number A
359
Residue number B
362
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 359 of Kinase suppressor of Ras 1
Cysteine 362 of Kinase suppressor of Ras 1
1kbf A 366 A 370
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 366 and 370. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
1kbf
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
10
% buried
8
Peptide accession
Q61097
Residue number A
366
Residue number B
370
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 366 of Kinase suppressor of Ras 1
Cysteine 370 of Kinase suppressor of Ras 1
1kbe A 362 A 366
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 362 and 366. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
1kbe
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
49
Minimum pKa ?
10
% buried
8
Peptide accession
Q61097
Residue number A
362
Residue number B
366
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 362 of Kinase suppressor of Ras 1
Cysteine 366 of Kinase suppressor of Ras 1
1kbf A 349 A 366
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 349 and 366. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
1kbf
Structure name
solution structure of the cysteine-rich c1 domain of kinase suppressor of ras
Structure deposition date
2001-11-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
56
Minimum pKa ?
9
% buried
8
Peptide accession
Q61097
Residue number A
349
Residue number B
366
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 349 of Kinase suppressor of Ras 1
Cysteine 366 of Kinase suppressor of Ras 1
2lpe A 39 A 83
A redox-regulated disulphide may form within Kinase suppressor of Ras 1 between cysteines 39 and 83. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
2lpe
Structure name
solution nmr structure of the ksr1 ca1-ca1a domain
Structure deposition date
2012-02-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
72
Minimum pKa ?
10
% buried
65
Peptide accession
Q61097
Residue number A
39
Residue number B
83
Peptide name
Kinase suppressor of Ras 1
Ligandability
Cysteine 39 of Kinase suppressor of Ras 1
Cysteine 83 of Kinase suppressor of Ras 1
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