ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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SMC5-SMC6 complex localization factor protein 2

Intramolecular
Cysteine 983 and cysteine 1016
A redox-regulated disulphide may form within SMC5-SMC6 complex localization factor protein 2 between cysteines 983 and 1016.

Details

Redox score ?
69
PDB code
7t5p
Structure name
cryo-em structure of human simc1-slf2 complex
Structure deposition date
2021-12-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
65
Minimum pKa ?
7
% buried
58
Peptide accession
Q8IX21
Residue number A
983
Residue number B
1016
Peptide name
SMC5-SMC6 complex localization factor protein 2

Ligandability

Cysteine 983 of SMC5-SMC6 complex localization factor protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1016 of SMC5-SMC6 complex localization factor protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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