Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Intramolecular
Cysteine 136 and cysteine 140
Cysteine 105 and cysteine 136 L
Cysteine 105 and cysteine 140 L
Cysteine 100 and cysteine 136 L
Cysteine 100 and cysteine 140 L
Cysteine 100 and cysteine 105 L
7b7u M 136 M 140
A redox-regulated disulphide may form within Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 between cysteines 136 and 140.
Details
Redox score ?
81
PDB code
7b7u
Structure name
cryo-em structure of mammalian rna polymerase ii in complex with human rpap2
Structure deposition date
2020-12-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
6
% buried
32
Peptide accession
Q8IXW5
Residue number A
136
Residue number B
140
Peptide name
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Ligandability
Cysteine 136 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Cysteine 140 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
7b7u M 105 M 136
A redox-regulated disulphide may form within Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 between cysteines 105 and 136.
Details
Redox score ?
80
PDB code
7b7u
Structure name
cryo-em structure of mammalian rna polymerase ii in complex with human rpap2
Structure deposition date
2020-12-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
6
% buried
34
Peptide accession
Q8IXW5
Residue number A
105
Residue number B
136
Peptide name
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Ligandability
Cysteine 105 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Cysteine 136 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
7b7u M 105 M 140
A redox-regulated disulphide may form within Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 between cysteines 105 and 140.
Details
Redox score ?
79
PDB code
7b7u
Structure name
cryo-em structure of mammalian rna polymerase ii in complex with human rpap2
Structure deposition date
2020-12-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
8
% buried
38
Peptide accession
Q8IXW5
Residue number A
105
Residue number B
140
Peptide name
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Ligandability
Cysteine 105 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Cysteine 140 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
7b7u M 100 M 136
A redox-regulated disulphide may form within Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 between cysteines 100 and 136.
Details
Redox score ?
79
PDB code
7b7u
Structure name
cryo-em structure of mammalian rna polymerase ii in complex with human rpap2
Structure deposition date
2020-12-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
70
Minimum pKa ?
6
% buried
46
Peptide accession
Q8IXW5
Residue number A
100
Residue number B
136
Peptide name
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Ligandability
Cysteine 100 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Cysteine 136 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
7b7u M 100 M 140
A redox-regulated disulphide may form within Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 between cysteines 100 and 140.
Details
Redox score ?
77
PDB code
7b7u
Structure name
cryo-em structure of mammalian rna polymerase ii in complex with human rpap2
Structure deposition date
2020-12-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
65
Minimum pKa ?
8
% buried
50
Peptide accession
Q8IXW5
Residue number A
100
Residue number B
140
Peptide name
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Ligandability
Cysteine 100 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Cysteine 140 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
7b7u M 100 M 105
A redox-regulated disulphide may form within Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 between cysteines 100 and 105.
Details
Redox score ?
72
PDB code
7b7u
Structure name
cryo-em structure of mammalian rna polymerase ii in complex with human rpap2
Structure deposition date
2020-12-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
10
% buried
52
Peptide accession
Q8IXW5
Residue number A
100
Residue number B
105
Peptide name
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Ligandability
Cysteine 100 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Cysteine 105 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
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