ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Exocyst complex component 8

Intermolecular
Cysteine 202 and cysteine 202
A redox-regulated disulphide may form between two units of Exocyst complex component 8 at cysteines 202 and 202. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
1zc3
Structure name
crystal structure of the ral-binding domain of exo84 in complex with the active rala
Structure deposition date
2005-04-10
Thiol separation (Å)
6
Half-sphere exposure sum ?
75
Minimum pKa ?
14
% buried
94
Peptide A name
Exocyst complex component 8
Peptide B name
Exocyst complex component 8
Peptide A accession
O54924
Peptide B accession
O54924
Peptide A residue number
202
Peptide B residue number
202

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: