ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Calcium uptake protein 2, mitochondrial

Intermolecular
Cysteine 413 and cysteine 463 of Calcium uptake protein 1, mitochondrial
A redox-regulated disulphide is known to form between cysteine 413 of Calcium uptake protein 2, mitochondrial and cysteine 463 of Calcium uptake protein 1, mitochondrial.

Details

Redox score ?
85
PDB code
6wdn
Structure name
cryo-em structure of mitochondrial calcium uniporter holocomplex in low ca2+
Structure deposition date
2020-04-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide A name
Calcium uptake protein 2, mitochondrial
Peptide B name
Calcium uptake protein 1, mitochondrial
Peptide A accession
Q8IYU8
Peptide B accession
Q9BPX6
Peptide A residue number
413
Peptide B residue number
463

Ligandability

Cysteine 413 of Calcium uptake protein 2, mitochondrial

Cysteine 463 of Calcium uptake protein 1, mitochondrial

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