ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

RING finger protein 113B

Intramolecular
Cysteine 256 and cysteine 259
Cysteine 290 and cysteine 293
Cysteine 256 and cysteine 276
Cysteine 256 and cysteine 279
Cysteine 271 and cysteine 290
Cysteine 271 and cysteine 293
Cysteine 259 and cysteine 279
Cysteine 259 and cysteine 276
Cysteine 276 and cysteine 279
A redox-regulated disulphide may form within RING finger protein 113B between cysteines 256 and 259 (18 and 21 respectively in this structure).

Details

Redox score ?
90
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
3
Half-sphere exposure sum ?
43
Minimum pKa ?
6
% buried
10
Peptide accession
Q8IZP6
Residue number A
256
Residue number B
259
Peptide name
RING finger protein 113B

Ligandability

Cysteine 256 of RING finger protein 113B

Cysteine 259 of RING finger protein 113B

A redox-regulated disulphide may form within RING finger protein 113B between cysteines 290 and 293 (52 and 55 respectively in this structure).

Details

Redox score ?
88
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
5
% buried
14
Peptide accession
Q8IZP6
Residue number A
290
Residue number B
293
Peptide name
RING finger protein 113B

Ligandability

Cysteine 290 of RING finger protein 113B

Cysteine 293 of RING finger protein 113B

A redox-regulated disulphide may form within RING finger protein 113B between cysteines 256 and 276 (18 and 38 respectively in this structure).

Details

Redox score ?
86
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
3
Half-sphere exposure sum ?
59
Minimum pKa ?
6
% buried
20
Peptide accession
Q8IZP6
Residue number A
256
Residue number B
276
Peptide name
RING finger protein 113B

Ligandability

Cysteine 256 of RING finger protein 113B

Cysteine 276 of RING finger protein 113B

A redox-regulated disulphide may form within RING finger protein 113B between cysteines 256 and 279 (18 and 41 respectively in this structure).

Details

Redox score ?
85
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
6
% buried
18
Peptide accession
Q8IZP6
Residue number A
256
Residue number B
279
Peptide name
RING finger protein 113B

Ligandability

Cysteine 256 of RING finger protein 113B

Cysteine 279 of RING finger protein 113B

A redox-regulated disulphide may form within RING finger protein 113B between cysteines 271 and 290 (33 and 52 respectively in this structure).

Details

Redox score ?
85
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
5
% buried
24
Peptide accession
Q8IZP6
Residue number A
271
Residue number B
290
Peptide name
RING finger protein 113B

Ligandability

Cysteine 271 of RING finger protein 113B

Cysteine 290 of RING finger protein 113B

A redox-regulated disulphide may form within RING finger protein 113B between cysteines 271 and 293 (33 and 55 respectively in this structure).

Details

Redox score ?
83
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
36
Minimum pKa ?
9
% buried
10
Peptide accession
Q8IZP6
Residue number A
271
Residue number B
293
Peptide name
RING finger protein 113B

Ligandability

Cysteine 271 of RING finger protein 113B

Cysteine 293 of RING finger protein 113B

A redox-regulated disulphide may form within RING finger protein 113B between cysteines 259 and 279 (21 and 41 respectively in this structure).

Details

Redox score ?
79
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
8
% buried
8
Peptide accession
Q8IZP6
Residue number A
259
Residue number B
279
Peptide name
RING finger protein 113B

Ligandability

Cysteine 259 of RING finger protein 113B

Cysteine 279 of RING finger protein 113B

A redox-regulated disulphide may form within RING finger protein 113B between cysteines 259 and 276 (21 and 38 respectively in this structure).

Details

Redox score ?
77
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
8
% buried
10
Peptide accession
Q8IZP6
Residue number A
259
Residue number B
276
Peptide name
RING finger protein 113B

Ligandability

Cysteine 259 of RING finger protein 113B

Cysteine 276 of RING finger protein 113B

A redox-regulated disulphide may form within RING finger protein 113B between cysteines 276 and 279 (38 and 41 respectively in this structure).

Details

Redox score ?
71
PDB code
2csy
Structure name
solution structure of the ring domain of the zinc finger protein 183- like 1
Structure deposition date
2005-05-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
10
% buried
18
Peptide accession
Q8IZP6
Residue number A
276
Residue number B
279
Peptide name
RING finger protein 113B

Ligandability

Cysteine 276 of RING finger protein 113B

Cysteine 279 of RING finger protein 113B

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