ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Citramalyl-CoA lyase, mitochondrial

Intramolecular
Cysteine 69 and cysteine 105
A redox-regulated disulphide may form within Citramalyl-CoA lyase, mitochondrial between cysteines 69 and 105.

Details

Redox score ?
67
PDB code
5vxo
Structure name
crystal structure analysis of human clybl in complex with propionyl- coa
Structure deposition date
2017-05-23
Thiol separation (Å)
3
Half-sphere exposure sum ?
78
Minimum pKa ?
10
% buried
100
Peptide accession
Q8N0X4
Residue number A
69
Residue number B
105
Peptide name
Citramalyl-CoA lyase, mitochondrial

Ligandability

Cysteine 69 of Citramalyl-CoA lyase, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 105 of Citramalyl-CoA lyase, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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