ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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C-type lectin domain family 4 member F

Intramolecular
Cysteine 516 and cysteine 528
Cysteine 440 and cysteine 536
A redox-regulated disulphide may form within C-type lectin domain family 4 member F between cysteines 516 and 528.

Details

Redox score ?
81
PDB code
6jjj
Structure name
trimeric structure of kupffer cell c-type lectin receptor clec4f
Structure deposition date
2019-02-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70194
Residue number A
516
Residue number B
528
Peptide name
C-type lectin domain family 4 member F

Ligandability

Cysteine 516 of C-type lectin domain family 4 member F

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 528 of C-type lectin domain family 4 member F

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within C-type lectin domain family 4 member F between cysteines 440 and 536.

Details

Redox score ?
80
PDB code
6jjj
Structure name
trimeric structure of kupffer cell c-type lectin receptor clec4f
Structure deposition date
2019-02-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
P70194
Residue number A
440
Residue number B
536
Peptide name
C-type lectin domain family 4 member F

Ligandability

Cysteine 440 of C-type lectin domain family 4 member F

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 536 of C-type lectin domain family 4 member F

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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