a tool for identifying drug-targetable redox-active disulphides

Cell adhesion molecule 2

Intramolecular

Cysteine 44 and cysteine 104

A redox-regulated disulphide may form within Cell adhesion molecule 2 between cysteines 44 and 104 (53 and 113 respectively in this structure).

Details

Redox score ?

81

PDB code

Structure name

crystal structure of ig1 domain of mouse syncam 2

Structure deposition date

2010-03-10

Thiol separation (Å)

2

Half-sphere exposure sum ?

82

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

44

Residue number B

104

Peptide name

Cell adhesion molecule 2

Ligandability

Cysteine 44 of Cell adhesion molecule 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 104 of Cell adhesion molecule 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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