Leukocyte immunoglobulin-like receptor subfamily B member 2
Intramolecular
Cysteine 156 and cysteine 166
Cysteine 49 and cysteine 98
Cysteine 245 and cysteine 296
Cysteine 144 and cysteine 196
Cysteine 345 and cysteine 396
Cysteine 156 and cysteine 196
Cysteine 144 and cysteine 156
2gw5 A 134 A 144
A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily B member 2 between cysteines 156 and 166 (134 and 144 respectively in this structure).
Details
Redox score ?
85
PDB code
2gw5
Structure name
crystal structure of lir-2 (ilt4) at 1
Structure deposition date
2006-05-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N423
Residue number A
156
Residue number B
166
Peptide name
Leukocyte immunoglobulin-like receptor subfamily B member 2
Ligandability
Cysteine 156 of Leukocyte immunoglobulin-like receptor subfamily B member 2
Cysteine 166 of Leukocyte immunoglobulin-like receptor subfamily B member 2
2dyp D 26 D 75
A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily B member 2 between cysteines 49 and 98 (26 and 75 respectively in this structure).
Details
Redox score ?
83
PDB code
2dyp
Structure name
crystal structure of lilrb2(lir2/ilt4/cd85d) complexed with hla-g
Structure deposition date
2006-09-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N423
Residue number A
49
Residue number B
98
Peptide name
Leukocyte immunoglobulin-like receptor subfamily B member 2
Ligandability
Cysteine 49 of Leukocyte immunoglobulin-like receptor subfamily B member 2
Cysteine 98 of Leukocyte immunoglobulin-like receptor subfamily B member 2
4lla A 27 A 78
A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily B member 2 between cysteines 245 and 296 (27 and 78 respectively in this structure).
Details
Redox score ?
81
PDB code
4lla
Structure name
crystal structure of d3d4 domain of the lilrb2 molecule
Structure deposition date
2013-07-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N423
Residue number A
245
Residue number B
296
Peptide name
Leukocyte immunoglobulin-like receptor subfamily B member 2
Ligandability
Cysteine 245 of Leukocyte immunoglobulin-like receptor subfamily B member 2
Cysteine 296 of Leukocyte immunoglobulin-like receptor subfamily B member 2
2gw5 A 122 A 174
A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily B member 2 between cysteines 144 and 196 (122 and 174 respectively in this structure).
Details
Redox score ?
81
PDB code
2gw5
Structure name
crystal structure of lir-2 (ilt4) at 1
Structure deposition date
2006-05-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N423
Residue number A
144
Residue number B
196
Peptide name
Leukocyte immunoglobulin-like receptor subfamily B member 2
Ligandability
Cysteine 144 of Leukocyte immunoglobulin-like receptor subfamily B member 2
Cysteine 196 of Leukocyte immunoglobulin-like receptor subfamily B member 2
4lla C 127 C 178
A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily B member 2 between cysteines 345 and 396 (127 and 178 respectively in this structure).
Details
Redox score ?
80
PDB code
4lla
Structure name
crystal structure of d3d4 domain of the lilrb2 molecule
Structure deposition date
2013-07-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N423
Residue number A
345
Residue number B
396
Peptide name
Leukocyte immunoglobulin-like receptor subfamily B member 2
Ligandability
Cysteine 345 of Leukocyte immunoglobulin-like receptor subfamily B member 2
Cysteine 396 of Leukocyte immunoglobulin-like receptor subfamily B member 2
2gw5 A 134 A 174
A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily B member 2 between cysteines 156 and 196 (134 and 174 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
2gw5
Structure name
crystal structure of lir-2 (ilt4) at 1
Structure deposition date
2006-05-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N423
Residue number A
156
Residue number B
196
Peptide name
Leukocyte immunoglobulin-like receptor subfamily B member 2
Ligandability
Cysteine 156 of Leukocyte immunoglobulin-like receptor subfamily B member 2
Cysteine 196 of Leukocyte immunoglobulin-like receptor subfamily B member 2
6aed A 122 A 134
A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily B member 2 between cysteines 144 and 156 (122 and 134 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
6aed
Structure name
crystal structure of the four ig-like domain of lilrb2(lir2/ilt4/cd85d)
Structure deposition date
2018-08-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N423
Residue number A
144
Residue number B
156
Peptide name
Leukocyte immunoglobulin-like receptor subfamily B member 2
Ligandability
Cysteine 144 of Leukocyte immunoglobulin-like receptor subfamily B member 2
Cysteine 156 of Leukocyte immunoglobulin-like receptor subfamily B member 2
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