Ligand of Numb protein X 2
Intramolecular
Cysteine 120 and cysteine 137
Cysteine 114 and cysteine 137
Cysteine 50 and cysteine 53
Cysteine 53 and cysteine 73
Cysteine 114 and cysteine 120
Cysteine 53 and cysteine 70
Cysteine 65 and cysteine 84
Cysteine 23 and cysteine 26
Cysteine 50 and cysteine 70
Cysteine 70 and cysteine 73
More...Cysteine 65 and cysteine 96
Cysteine 84 and cysteine 96
Cysteine 50 and cysteine 73
5din A 101 A 118
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 120 and 137 (101 and 118 respectively in this structure).
Details
Redox score ?
89
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
7
% buried
0
Peptide accession
Q8N448
Residue number A
120
Residue number B
137
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 120 of Ligand of Numb protein X 2
Cysteine 137 of Ligand of Numb protein X 2
5din A 95 A 118
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 114 and 137 (95 and 118 respectively in this structure).
Details
Redox score ?
86
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
7
% buried
10
Peptide accession
Q8N448
Residue number A
114
Residue number B
137
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 114 of Ligand of Numb protein X 2
Cysteine 137 of Ligand of Numb protein X 2
5din A 31 A 34
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 50 and 53 (31 and 34 respectively in this structure).
Details
Redox score ?
83
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
6
% buried
nan
Peptide accession
Q8N448
Residue number A
50
Residue number B
53
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 50 of Ligand of Numb protein X 2
Cysteine 53 of Ligand of Numb protein X 2
5din B 34 B 54
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 53 and 73 (34 and 54 respectively in this structure).
Details
Redox score ?
83
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
6
% buried
51
Peptide accession
Q8N448
Residue number A
53
Residue number B
73
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 53 of Ligand of Numb protein X 2
Cysteine 73 of Ligand of Numb protein X 2
5din A 95 A 101
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 114 and 120 (95 and 101 respectively in this structure).
Details
Redox score ?
81
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
9
% buried
10
Peptide accession
Q8N448
Residue number A
114
Residue number B
120
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 114 of Ligand of Numb protein X 2
Cysteine 120 of Ligand of Numb protein X 2
5din B 34 B 51
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 53 and 70 (34 and 51 respectively in this structure).
Details
Redox score ?
81
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
6
% buried
63
Peptide accession
Q8N448
Residue number A
53
Residue number B
70
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 53 of Ligand of Numb protein X 2
Cysteine 70 of Ligand of Numb protein X 2
5din B 46 B 65
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 65 and 84 (46 and 65 respectively in this structure).
Details
Redox score ?
80
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
8
% buried
29
Peptide accession
Q8N448
Residue number A
65
Residue number B
84
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 65 of Ligand of Numb protein X 2
Cysteine 84 of Ligand of Numb protein X 2
5din B 4 B 7
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 23 and 26 (4 and 7 respectively in this structure).
Details
Redox score ?
76
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
8
% buried
36
Peptide accession
Q8N448
Residue number A
23
Residue number B
26
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 23 of Ligand of Numb protein X 2
Cysteine 26 of Ligand of Numb protein X 2
5din B 31 B 51
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 50 and 70 (31 and 51 respectively in this structure).
Details
Redox score ?
65
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
14
% buried
nan
Peptide accession
Q8N448
Residue number A
50
Residue number B
70
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 50 of Ligand of Numb protein X 2
Cysteine 70 of Ligand of Numb protein X 2
5din B 51 B 54
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 70 and 73 (51 and 54 respectively in this structure).
Details
Redox score ?
61
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
14
% buried
66
Peptide accession
Q8N448
Residue number A
70
Residue number B
73
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 70 of Ligand of Numb protein X 2
Cysteine 73 of Ligand of Numb protein X 2
5din B 46 B 77
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 65 and 96 (46 and 77 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
8
Half-sphere exposure sum ?
52
Minimum pKa ?
8
% buried
35
Peptide accession
Q8N448
Residue number A
65
Residue number B
96
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 65 of Ligand of Numb protein X 2
Cysteine 96 of Ligand of Numb protein X 2
5din B 65 B 77
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 84 and 96 (65 and 77 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
9
Half-sphere exposure sum ?
55
Minimum pKa ?
11
% buried
38
Peptide accession
Q8N448
Residue number A
84
Residue number B
96
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 84 of Ligand of Numb protein X 2
Cysteine 96 of Ligand of Numb protein X 2
5din A 31 A 54
A redox-regulated disulphide may form within Ligand of Numb protein X 2 between cysteines 50 and 73 (31 and 54 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
5din
Structure name
structural basis for the indispensable role of a unique zinc finger motif in lnx2 ubiquitination
Structure deposition date
2015-09-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
23
% buried
nan
Peptide accession
Q8N448
Residue number A
50
Residue number B
73
Peptide name
Ligand of Numb protein X 2
Ligandability
Cysteine 50 of Ligand of Numb protein X 2
Cysteine 73 of Ligand of Numb protein X 2
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