Mitochondrial intermembrane space import and assembly protein 40

Intramolecular

A redox-regulated disulphide may form within Mitochondrial intermembrane space import and assembly protein 40 between cysteines 64 and 97 (19 and 52 respectively in this structure).

Details

Redox score ?

PDB code

2l0y

Structure name

complex hmia40-hcox17

Structure deposition date

2010-07-20

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q8N4Q1

Residue number A

Residue number B

Peptide name

Mitochondrial intermembrane space import and assembly protein 40

Ligandability

Cysteine 64 of Mitochondrial intermembrane space import and assembly protein 40

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 97 of Mitochondrial intermembrane space import and assembly protein 40

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Mitochondrial intermembrane space import and assembly protein 40 between cysteines 74 and 87 (78 and 91 respectively in this structure).

Details

Redox score ?

PDB code

2k3j

Structure name

the solution structure of human mia40

Structure deposition date

2008-05-08

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q8N4Q1

Residue number A

Residue number B

Peptide name

Mitochondrial intermembrane space import and assembly protein 40

Ligandability

Cysteine 74 of Mitochondrial intermembrane space import and assembly protein 40

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 87 of Mitochondrial intermembrane space import and assembly protein 40

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Mitochondrial intermembrane space import and assembly protein 40 between cysteines 53 and 55 (57 and 59 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?