ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Fibrinogen C domain-containing protein 1

Intramolecular
Cysteine 244 and cysteine 273
Cysteine 401 and cysteine 414
A redox-regulated disulphide may form within Fibrinogen C domain-containing protein 1 between cysteines 244 and 273.

Details

Redox score ?
83
PDB code
4m7f
Structure name
crystal structure of tetrameric fibrinogen-like recognition domain of fibcd1 with bound mannac
Structure deposition date
2013-08-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N539
Residue number A
244
Residue number B
273
Peptide name
Fibrinogen C domain-containing protein 1

Ligandability

Cysteine 244 of Fibrinogen C domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 273 of Fibrinogen C domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Fibrinogen C domain-containing protein 1 between cysteines 401 and 414.

Details

Redox score ?
82
PDB code
4m7f
Structure name
crystal structure of tetrameric fibrinogen-like recognition domain of fibcd1 with bound mannac
Structure deposition date
2013-08-12
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N539
Residue number A
401
Residue number B
414
Peptide name
Fibrinogen C domain-containing protein 1

Ligandability

Cysteine 401 of Fibrinogen C domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 414 of Fibrinogen C domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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