ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Leukocyte immunoglobulin-like receptor subfamily A member 3

Intramolecular
Cysteine 49 and cysteine 98
Cysteine 97 and cysteine 98
Cysteine 49 and cysteine 97
A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily A member 3 between cysteines 49 and 98 (26 and 75 respectively in this structure).

Details

Redox score ?
82
PDB code
3q2c
Structure name
binding properties to hla class i molecules and the structure of the leukocyte ig-like receptor a3 (lilra3/ilt6/lir4/cd85e)
Structure deposition date
2010-12-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8N6C8
Residue number A
49
Residue number B
98
Peptide name
Leukocyte immunoglobulin-like receptor subfamily A member 3

Ligandability

Cysteine 49 of Leukocyte immunoglobulin-like receptor subfamily A member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 98 of Leukocyte immunoglobulin-like receptor subfamily A member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily A member 3 between cysteines 97 and 98 (74 and 75 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
3q2c
Structure name
binding properties to hla class i molecules and the structure of the leukocyte ig-like receptor a3 (lilra3/ilt6/lir4/cd85e)
Structure deposition date
2010-12-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
72
Minimum pKa ?
10
% buried
nan
Peptide accession
Q8N6C8
Residue number A
97
Residue number B
98
Peptide name
Leukocyte immunoglobulin-like receptor subfamily A member 3

Ligandability

Cysteine 97 of Leukocyte immunoglobulin-like receptor subfamily A member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 98 of Leukocyte immunoglobulin-like receptor subfamily A member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Leukocyte immunoglobulin-like receptor subfamily A member 3 between cysteines 49 and 97 (26 and 74 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
33
PDB code
3q2c
Structure name
binding properties to hla class i molecules and the structure of the leukocyte ig-like receptor a3 (lilra3/ilt6/lir4/cd85e)
Structure deposition date
2010-12-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
75
Minimum pKa ?
10
% buried
nan
Peptide accession
Q8N6C8
Residue number A
49
Residue number B
97
Peptide name
Leukocyte immunoglobulin-like receptor subfamily A member 3

Ligandability

Cysteine 49 of Leukocyte immunoglobulin-like receptor subfamily A member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 97 of Leukocyte immunoglobulin-like receptor subfamily A member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: