a tool for identifying drug-targetable redox-active disulphides

Peroxisomal succinyl-coenzyme A thioesterase

Intramolecular

Cysteine 13 and cysteine 14

A redox-regulated disulphide may form within Peroxisomal succinyl-coenzyme A thioesterase between cysteines 13 and 14.

Details

Redox score ?

62

PDB code

Structure name

human acyl-coenzyme a thioesterase 4

Structure deposition date

2009-09-30

Thiol separation (Å)

7

Half-sphere exposure sum ?

nan

Minimum pK_a ?

10

% buried

44

Peptide accession

Residue number A

13

Residue number B

14

Peptide name

Peroxisomal succinyl-coenzyme A thioesterase

Ligandability

Cysteine 13 of Peroxisomal succinyl-coenzyme A thioesterase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 14 of Peroxisomal succinyl-coenzyme A thioesterase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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