ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Pre-mRNA-splicing factor 38A

Intramolecular
Cysteine 39 and cysteine 72
A redox-regulated disulphide may form within Pre-mRNA-splicing factor 38A between cysteines 39 and 72. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
55
PDB code
4rz9
Structure name
pre-mrna-splicing factor 38a as 1-179
Structure deposition date
2014-12-19
Thiol separation (Å)
6
Half-sphere exposure sum ?
76
Minimum pKa ?
12
% buried
81
Peptide accession
Q8NAV1
Residue number A
39
Residue number B
72
Peptide name
Pre-mRNA-splicing factor 38A

Ligandability

Cysteine 39 of Pre-mRNA-splicing factor 38A

Cysteine 72 of Pre-mRNA-splicing factor 38A

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