NHL repeat-containing protein 2
Intramolecular
Cysteine 90 and cysteine 93
Cysteine 89 and cysteine 90
Cysteine 90 and cysteine 161
Cysteine 93 and cysteine 161
Cysteine 89 and cysteine 93
6gc1 B 90 B 93
A redox-regulated disulphide may form within NHL repeat-containing protein 2 between cysteines 90 and 93.
Details
Redox score ?
66
PDB code
6gc1
Structure name
crystal structure of trx-like and nhl repeat containing domains of human nhlrc2
Structure deposition date
2018-04-16
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
100
Peptide accession
Q8NBF2
Residue number A
90
Residue number B
93
Peptide name
NHL repeat-containing protein 2
Ligandability
Cysteine 90 of NHL repeat-containing protein 2
Cysteine 93 of NHL repeat-containing protein 2
6gc1 A 89 A 90
A redox-regulated disulphide may form within NHL repeat-containing protein 2 between cysteines 89 and 90. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
6gc1
Structure name
crystal structure of trx-like and nhl repeat containing domains of human nhlrc2
Structure deposition date
2018-04-16
Thiol separation (Å)
6
Half-sphere exposure sum ?
76
Minimum pKa ?
10
% buried
100
Peptide accession
Q8NBF2
Residue number A
89
Residue number B
90
Peptide name
NHL repeat-containing protein 2
Ligandability
Cysteine 89 of NHL repeat-containing protein 2
Cysteine 90 of NHL repeat-containing protein 2
6gc1 A 90 A 161
A redox-regulated disulphide may form within NHL repeat-containing protein 2 between cysteines 90 and 161. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
6gc1
Structure name
crystal structure of trx-like and nhl repeat containing domains of human nhlrc2
Structure deposition date
2018-04-16
Thiol separation (Å)
8
Half-sphere exposure sum ?
65
Minimum pKa ?
10
% buried
87
Peptide accession
Q8NBF2
Residue number A
90
Residue number B
161
Peptide name
NHL repeat-containing protein 2
Ligandability
Cysteine 90 of NHL repeat-containing protein 2
Cysteine 161 of NHL repeat-containing protein 2
6gc1 C 93 C 161
A redox-regulated disulphide may form within NHL repeat-containing protein 2 between cysteines 93 and 161. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
6gc1
Structure name
crystal structure of trx-like and nhl repeat containing domains of human nhlrc2
Structure deposition date
2018-04-16
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
11
% buried
84
Peptide accession
Q8NBF2
Residue number A
93
Residue number B
161
Peptide name
NHL repeat-containing protein 2
Ligandability
Cysteine 93 of NHL repeat-containing protein 2
Cysteine 161 of NHL repeat-containing protein 2
6gc1 A 89 A 93
A redox-regulated disulphide may form within NHL repeat-containing protein 2 between cysteines 89 and 93. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
6gc1
Structure name
crystal structure of trx-like and nhl repeat containing domains of human nhlrc2
Structure deposition date
2018-04-16
Thiol separation (Å)
7
Half-sphere exposure sum ?
73
Minimum pKa ?
18
% buried
100
Peptide accession
Q8NBF2
Residue number A
89
Residue number B
93
Peptide name
NHL repeat-containing protein 2
Ligandability
Cysteine 89 of NHL repeat-containing protein 2
Cysteine 93 of NHL repeat-containing protein 2
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