a tool for identifying drug-targetable redox-active disulphides

NFATC2-interacting protein

Intramolecular

Cysteine 271 and cysteine 332

A redox-regulated disulphide may form within NFATC2-interacting protein between cysteines 271 and 332.

Details

Redox score ?

62

PDB code

Structure name

solution nmr structure of human nfatc2ip ubiquitin-like domain, nfatc2ip_244_338, nesg target ht65a/ocsp target hs00387_244_338/sgc- toronto

Structure deposition date

2010-12-03

Thiol separation (Å)

7

Half-sphere exposure sum ?

66

Minimum pK_a ?

9

% buried

22

Peptide accession

Residue number A

271

Residue number B

332

Peptide name

NFATC2-interacting protein

Ligandability

Cysteine 271 of NFATC2-interacting protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 332 of NFATC2-interacting protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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