ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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E3 ubiquitin-protein ligase RNF169

Intermolecular
Cysteine 626 and cysteine 626
A redox-regulated disulphide may form between two units of E3 ubiquitin-protein ligase RNF169 at cysteines 626 and 626.

Details

Redox score ?
82
PDB code
5gg4
Structure name
crystal structure of usp7 with rnf169 peptide
Structure deposition date
2016-06-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
58
Minimum pKa ?
7
% buried
62
Peptide A name
E3 ubiquitin-protein ligase RNF169
Peptide B name
E3 ubiquitin-protein ligase RNF169
Peptide A accession
Q8NCN4
Peptide B accession
Q8NCN4
Peptide A residue number
626
Peptide B residue number
626

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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