Nucleoporin Nup43

Intramolecular

A redox-regulated disulphide may form within Nucleoporin Nup43 between cysteines 280 and 365. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4i79

Structure name

crystal structure of human nup43

Structure deposition date

2012-11-30

Thiol separation (Å)

Half-sphere exposure sum ?

100

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q8NFH3

Residue number A

280

Residue number B

365

Peptide name

Nucleoporin Nup43

Ligandability

Cysteine 280 of Nucleoporin Nup43

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 365 of Nucleoporin Nup43

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Nucleoporin Nup43 between cysteines 222 and 280. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4i79

Structure name

crystal structure of human nup43

Structure deposition date

2012-11-30

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q8NFH3

Residue number A

222

Residue number B

280

Peptide name

Nucleoporin Nup43

Ligandability

Cysteine 222 of Nucleoporin Nup43

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 280 of Nucleoporin Nup43

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Nucleoporin Nup43 between cysteines 96 and 134. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?