Inositol polyphosphate multikinase

Intramolecular

A redox-regulated disulphide may form within Inositol polyphosphate multikinase between cysteines 141 and 220. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6e7f

Structure name

crystal structure of human inositol polyphosphate multikinase (ipmk) catalytic core domain

Structure deposition date

2018-07-26

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q8NFU5

Residue number A

141

Residue number B

220

Peptide name

Inositol polyphosphate multikinase

Ligandability

Cysteine 141 of Inositol polyphosphate multikinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.