ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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V-type proton ATPase subunit e 2

Intramolecular
Cysteine 47 and cysteine 48
A redox-regulated disulphide may form within V-type proton ATPase subunit e 2 between cysteines 47 and 48.

Details

Redox score ?
66
PDB code
6vqg
Structure name
mammalian v-atpase from rat brain membrane-embedded vo region rotational state 2 (from focused refinement)
Structure deposition date
2020-02-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
9
% buried
95
Peptide accession
Q5EB76
Residue number A
47
Residue number B
48
Peptide name
V-type proton ATPase subunit e 2

Ligandability

Cysteine 47 of V-type proton ATPase subunit e 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 48 of V-type proton ATPase subunit e 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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