a tool for identifying drug-targetable redox-active disulphides

Rieske domain-containing protein

Intramolecular

Cysteine 57 and cysteine 80

A redox-regulated disulphide may form within Rieske domain-containing protein between cysteines 57 and 80.

Details

Redox score ?

77

PDB code

Structure name

crystal structure of a soluble rieske ferredoxin from mus musculus

Structure deposition date

2008-05-22

Thiol separation (Å)

4

Half-sphere exposure sum ?

76

Minimum pK_a ?

7

% buried

64

Peptide accession

Residue number A

57

Residue number B

80

Peptide name

Rieske domain-containing protein

Ligandability

Cysteine 57 of Rieske domain-containing protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 80 of Rieske domain-containing protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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