Endonuclease 8-like 3
Intramolecular
Cysteine 258 and cysteine 277
Cysteine 533 and cysteine 541
Cysteine 507 and cysteine 533
Cysteine 554 and cysteine 587
Cysteine 255 and cysteine 258
Cysteine 507 and cysteine 541
Cysteine 258 and cysteine 280
Cysteine 579 and cysteine 587
Cysteine 255 and cysteine 280
Cysteine 554 and cysteine 579
More...Cysteine 255 and cysteine 277
Cysteine 507 and cysteine 514
Cysteine 277 and cysteine 280
Cysteine 514 and cysteine 533
Cysteine 514 and cysteine 541
Cysteine 236 and cysteine 237
Cysteine 236 and cysteine 247
Cysteine 157 and cysteine 237
Cysteine 179 and cysteine 265
Cysteine 7 and cysteine 157
3w0f A 258 A 277
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 258 and 277.
Details
Redox score ?
89
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
3
Half-sphere exposure sum ?
54
Minimum pKa ?
5
% buried
6
Peptide accession
Q8K203
Residue number A
258
Residue number B
277
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 258 of Endonuclease 8-like 3
Cysteine 277 of Endonuclease 8-like 3
7jl5 A 533 A 541
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 533 and 541.
Details
Redox score ?
89
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
3
Half-sphere exposure sum ?
49
Minimum pKa ?
5
% buried
0
Peptide accession
Q8TAT5
Residue number A
533
Residue number B
541
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 533 of Endonuclease 8-like 3
Cysteine 541 of Endonuclease 8-like 3
7jl5 A 507 A 533
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 507 and 533.
Details
Redox score ?
88
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
5
% buried
0
Peptide accession
Q8TAT5
Residue number A
507
Residue number B
533
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 507 of Endonuclease 8-like 3
Cysteine 533 of Endonuclease 8-like 3
7jl5 A 554 A 587
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 554 and 587.
Details
Redox score ?
88
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
6
% buried
6
Peptide accession
Q8TAT5
Residue number A
554
Residue number B
587
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 554 of Endonuclease 8-like 3
Cysteine 587 of Endonuclease 8-like 3
3w0f A 255 A 258
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 255 and 258.
Details
Redox score ?
87
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
5
% buried
4
Peptide accession
Q8K203
Residue number A
255
Residue number B
258
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 255 of Endonuclease 8-like 3
Cysteine 258 of Endonuclease 8-like 3
7jl5 B 507 B 541
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 507 and 541.
Details
Redox score ?
87
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
5
% buried
0
Peptide accession
Q8TAT5
Residue number A
507
Residue number B
541
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 507 of Endonuclease 8-like 3
Cysteine 541 of Endonuclease 8-like 3
3w0f A 258 A 280
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 258 and 280.
Details
Redox score ?
86
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
5
% buried
2
Peptide accession
Q8K203
Residue number A
258
Residue number B
280
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 258 of Endonuclease 8-like 3
Cysteine 280 of Endonuclease 8-like 3
7jl5 A 579 A 587
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 579 and 587.
Details
Redox score ?
85
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
6
% buried
0
Peptide accession
Q8TAT5
Residue number A
579
Residue number B
587
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 579 of Endonuclease 8-like 3
Cysteine 587 of Endonuclease 8-like 3
3w0f A 255 A 280
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 255 and 280.
Details
Redox score ?
83
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
8
% buried
7
Peptide accession
Q8K203
Residue number A
255
Residue number B
280
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 255 of Endonuclease 8-like 3
Cysteine 280 of Endonuclease 8-like 3
7jl5 A 554 A 579
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 554 and 579.
Details
Redox score ?
82
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
8
% buried
6
Peptide accession
Q8TAT5
Residue number A
554
Residue number B
579
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 554 of Endonuclease 8-like 3
Cysteine 579 of Endonuclease 8-like 3
3w0f A 255 A 277
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 255 and 277.
Details
Redox score ?
81
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
8
% buried
11
Peptide accession
Q8K203
Residue number A
255
Residue number B
277
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 255 of Endonuclease 8-like 3
Cysteine 277 of Endonuclease 8-like 3
7jl5 A 507 A 514
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 507 and 514.
Details
Redox score ?
76
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
5
Half-sphere exposure sum ?
49
Minimum pKa ?
8
% buried
2
Peptide accession
Q8TAT5
Residue number A
507
Residue number B
514
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 507 of Endonuclease 8-like 3
Cysteine 514 of Endonuclease 8-like 3
3w0f A 277 A 280
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 277 and 280.
Details
Redox score ?
76
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
65
Minimum pKa ?
9
% buried
9
Peptide accession
Q8K203
Residue number A
277
Residue number B
280
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 277 of Endonuclease 8-like 3
Cysteine 280 of Endonuclease 8-like 3
7jl5 A 514 A 533
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 514 and 533.
Details
Redox score ?
71
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
56
Minimum pKa ?
5
% buried
2
Peptide accession
Q8TAT5
Residue number A
514
Residue number B
533
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 514 of Endonuclease 8-like 3
Cysteine 533 of Endonuclease 8-like 3
7jl5 A 514 A 541
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 514 and 541. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
60
PDB code
7jl5
Structure name
crystal structure of human neil3 tandem zinc finger grf domains
Structure deposition date
2020-07-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
49
Minimum pKa ?
10
% buried
2
Peptide accession
Q8TAT5
Residue number A
514
Residue number B
541
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 514 of Endonuclease 8-like 3
Cysteine 541 of Endonuclease 8-like 3
3w0f A 236 A 237
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 236 and 237. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
7
Half-sphere exposure sum ?
47
Minimum pKa ?
9
% buried
30
Peptide accession
Q8K203
Residue number A
236
Residue number B
237
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 236 of Endonuclease 8-like 3
Cysteine 237 of Endonuclease 8-like 3
3w0f A 236 A 247
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 236 and 247. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
28
Peptide accession
Q8K203
Residue number A
236
Residue number B
247
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 236 of Endonuclease 8-like 3
Cysteine 247 of Endonuclease 8-like 3
3w0f A 157 A 237
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 157 and 237. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
8
Half-sphere exposure sum ?
66
Minimum pKa ?
11
% buried
72
Peptide accession
Q8K203
Residue number A
157
Residue number B
237
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 157 of Endonuclease 8-like 3
Cysteine 237 of Endonuclease 8-like 3
3w0f A 179 A 265
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 179 and 265. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
10
% buried
39
Peptide accession
Q8K203
Residue number A
179
Residue number B
265
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 179 of Endonuclease 8-like 3
Cysteine 265 of Endonuclease 8-like 3
3w0f A 7 A 157
A redox-regulated disulphide may form within Endonuclease 8-like 3 between cysteines 7 and 157. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
29
PDB code
3w0f
Structure name
crystal structure of mouse endonuclease viii-like 3 (mneil3)
Structure deposition date
2012-10-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
86
Minimum pKa ?
13
% buried
96
Peptide accession
Q8K203
Residue number A
7
Residue number B
157
Peptide name
Endonuclease 8-like 3
Ligandability
Cysteine 7 of Endonuclease 8-like 3
Cysteine 157 of Endonuclease 8-like 3
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