ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ganglioside-induced differentiation-associated protein 1

Intermolecular
Cysteine 88 and cysteine 88
A redox-regulated disulphide may form between two units of Ganglioside-induced differentiation-associated protein 1 at cysteines 88 and 88.

Details

Redox score ?
77
PDB code
7ywd
Structure name
human gdap1 core domain, trigonal crystal form
Structure deposition date
2022-02-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
70
Minimum pKa ?
8
% buried
72
Peptide A name
Ganglioside-induced differentiation-associated protein 1
Peptide B name
Ganglioside-induced differentiation-associated protein 1
Peptide A accession
Q8TB36
Peptide B accession
Q8TB36
Peptide A residue number
88
Peptide B residue number
88

Ligandability

If this tool was useful for finding a disulphide, please cite: