ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Guanine nucleotide exchange factor for Rab-3A

Intermolecular
Cysteine 97 and cysteine 97
A redox-regulated disulphide may form between two units of Guanine nucleotide exchange factor for Rab-3A at cysteines 97 and 97.

Details

Redox score ?
70
PDB code
4li0
Structure name
crystal structure of gdp-bound rab8:grab
Structure deposition date
2013-07-01
Thiol separation (Å)
5
Half-sphere exposure sum ?
51
Minimum pKa ?
10
% buried
0
Peptide A name
Guanine nucleotide exchange factor for Rab-3A
Peptide B name
Guanine nucleotide exchange factor for Rab-3A
Peptide A accession
Q8TBN0
Peptide B accession
Q8TBN0
Peptide A residue number
97
Peptide B residue number
97

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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