a tool for identifying drug-targetable redox-active disulphides

Placental protein 13-like

Intramolecular

Cysteine 19 and cysteine 92

A redox-regulated disulphide may form within Placental protein 13-like between cysteines 19 and 92 (22 and 95 respectively in this structure).

Details

Redox score ?

67

PDB code

Structure name

human galectin-14

Structure deposition date

2019-05-15

Thiol separation (Å)

4

Half-sphere exposure sum ?

56

Minimum pK_a ?

11

% buried

39

Peptide accession

Residue number A

19

Residue number B

92

Peptide name

Placental protein 13-like

Ligandability

Cysteine 19 of Placental protein 13-like

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 92 of Placental protein 13-like

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: