Chromodomain-helicase-DNA-binding protein 5
Intermolecular
Cysteine 622 and cysteine 622
Intramolecular
Cysteine 434 and cysteine 457
Cysteine 431 and cysteine 460
Cysteine 431 and cysteine 457
Cysteine 431 and cysteine 434
Cysteine 419 and cysteine 422
Cysteine 434 and cysteine 460
Cysteine 419 and cysteine 442
Cysteine 422 and cysteine 442
Cysteine 457 and cysteine 460
More...Cysteine 430 and cysteine 431
Cysteine 457 and cysteine 462
Cysteine 460 and cysteine 462
Cysteine 430 and cysteine 434
6guu A 622 B 622
A redox-regulated disulphide may form between two units of Chromodomain-helicase-DNA-binding protein 5 at cysteines 622 and 622. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
7
Half-sphere exposure sum ?
67
Minimum pKa ?
12
% buried
74
Peptide A name
Chromodomain-helicase-DNA-binding protein 5
Peptide B name
Chromodomain-helicase-DNA-binding protein 5
Peptide A accession
Q8TDI0
Peptide B accession
Q8TDI0
Peptide A residue number
622
Peptide B residue number
622
Ligandability
6guu B 434 B 457
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 434 and 457.
Details
Redox score ?
87
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
53
Minimum pKa ?
5
% buried
22
Peptide accession
Q8TDI0
Residue number A
434
Residue number B
457
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 434 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 457 of Chromodomain-helicase-DNA-binding protein 5
6guu B 431 B 460
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 431 and 460.
Details
Redox score ?
86
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
7
% buried
4
Peptide accession
Q8TDI0
Residue number A
431
Residue number B
460
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 431 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 460 of Chromodomain-helicase-DNA-binding protein 5
6guu A 431 A 457
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 431 and 457.
Details
Redox score ?
84
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
7
% buried
20
Peptide accession
Q8TDI0
Residue number A
431
Residue number B
457
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 431 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 457 of Chromodomain-helicase-DNA-binding protein 5
6guu B 431 B 434
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 431 and 434.
Details
Redox score ?
84
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
7
% buried
8
Peptide accession
Q8TDI0
Residue number A
431
Residue number B
434
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 431 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 434 of Chromodomain-helicase-DNA-binding protein 5
6guu A 419 A 422
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 419 and 422.
Details
Redox score ?
84
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
7
% buried
7
Peptide accession
Q8TDI0
Residue number A
419
Residue number B
422
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 419 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 422 of Chromodomain-helicase-DNA-binding protein 5
6guu B 434 B 460
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 434 and 460.
Details
Redox score ?
82
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
42
Minimum pKa ?
9
% buried
4
Peptide accession
Q8TDI0
Residue number A
434
Residue number B
460
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 434 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 460 of Chromodomain-helicase-DNA-binding protein 5
6guu B 419 B 442
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 419 and 442.
Details
Redox score ?
81
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
6
% buried
13
Peptide accession
Q8TDI0
Residue number A
419
Residue number B
442
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 419 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 442 of Chromodomain-helicase-DNA-binding protein 5
6guu A 422 A 442
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 422 and 442.
Details
Redox score ?
79
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
9
% buried
0
Peptide accession
Q8TDI0
Residue number A
422
Residue number B
442
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 422 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 442 of Chromodomain-helicase-DNA-binding protein 5
6guu A 457 A 460
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 457 and 460.
Details
Redox score ?
78
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
16
Peptide accession
Q8TDI0
Residue number A
457
Residue number B
460
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 457 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 460 of Chromodomain-helicase-DNA-binding protein 5
6guu A 430 A 431
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 430 and 431. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
7
% buried
10
Peptide accession
Q8TDI0
Residue number A
430
Residue number B
431
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 430 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 431 of Chromodomain-helicase-DNA-binding protein 5
6guu A 457 A 462
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 457 and 462. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
28
Peptide accession
Q8TDI0
Residue number A
457
Residue number B
462
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 457 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 462 of Chromodomain-helicase-DNA-binding protein 5
6guu A 460 A 462
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 460 and 462. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
38
Minimum pKa ?
10
% buried
12
Peptide accession
Q8TDI0
Residue number A
460
Residue number B
462
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 460 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 462 of Chromodomain-helicase-DNA-binding protein 5
6guu B 430 B 434
A redox-regulated disulphide may form within Chromodomain-helicase-DNA-binding protein 5 between cysteines 430 and 434. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
6guu
Structure name
structure of chd5 phd2 - tandem chromodomains
Structure deposition date
2018-06-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
51
Minimum pKa ?
9
% buried
10
Peptide accession
Q8TDI0
Residue number A
430
Residue number B
434
Peptide name
Chromodomain-helicase-DNA-binding protein 5
Ligandability
Cysteine 430 of Chromodomain-helicase-DNA-binding protein 5
Cysteine 434 of Chromodomain-helicase-DNA-binding protein 5
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