ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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TRAF3-interacting protein 1

Intramolecular
Cysteine 114 and cysteine 115
A redox-regulated disulphide may form within TRAF3-interacting protein 1 between cysteines 114 and 115 (121 and 122 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
54
PDB code
2eqo
Structure name
solution structure of the stn_traf3ip1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [homo sapiens]
Structure deposition date
2007-03-30
Thiol separation (Å)
7
Half-sphere exposure sum ?
61
Minimum pKa ?
10
% buried
52
Peptide accession
Q8TDR0
Residue number A
114
Residue number B
115
Peptide name
TRAF3-interacting protein 1

Ligandability

Cysteine 114 of TRAF3-interacting protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 115 of TRAF3-interacting protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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