ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

G-protein coupled bile acid receptor 1

Intramolecular
Cysteine 85 and cysteine 155
A redox-regulated disulphide may form within G-protein coupled bile acid receptor 1 between cysteines 85 and 155.

Details

Redox score ?
82
PDB code
7bw0
Structure name
active human tgr5 complex with a synthetic agonist 23h
Structure deposition date
2020-04-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
9
% buried
7
Peptide accession
Q8TDU6
Residue number A
85
Residue number B
155
Peptide name
G-protein coupled bile acid receptor 1

Ligandability

Cysteine 85 of G-protein coupled bile acid receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 155 of G-protein coupled bile acid receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: