Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Intramolecular
Cysteine 444 and cysteine 461
Cysteine 461 and cysteine 464
Cysteine 441 and cysteine 461
Cysteine 444 and cysteine 464
Cysteine 441 and cysteine 444
Cysteine 441 and cysteine 464
Cysteine 441 and cysteine 442
Cysteine 637 and cysteine 670
Cysteine 442 and cysteine 464
Cysteine 442 and cysteine 444
2b0o F 444 F 461
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 444 and 461.
Details
Redox score ?
85
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
2
% buried
48
Peptide accession
Q6P9F4
Residue number A
444
Residue number B
461
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 444 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 461 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o G 461 G 464
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 461 and 464.
Details
Redox score ?
74
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
8
% buried
61
Peptide accession
Q6P9F4
Residue number A
461
Residue number B
464
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 461 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 464 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o G 441 G 461
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 441 and 461.
Details
Redox score ?
72
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
8
% buried
nan
Peptide accession
Q6P9F4
Residue number A
441
Residue number B
461
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 441 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 461 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o H 444 H 464
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 444 and 464.
Details
Redox score ?
64
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
81
Minimum pKa ?
13
% buried
57
Peptide accession
Q6P9F4
Residue number A
444
Residue number B
464
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 444 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 464 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o G 441 G 444
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 441 and 444.
Details
Redox score ?
64
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
13
% buried
nan
Peptide accession
Q6P9F4
Residue number A
441
Residue number B
444
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 441 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 444 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o E 441 E 464
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 441 and 464. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
80
Minimum pKa ?
21
% buried
nan
Peptide accession
Q6P9F4
Residue number A
441
Residue number B
464
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 441 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 464 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o E 441 E 442
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 441 and 442. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
7
Half-sphere exposure sum ?
83
Minimum pKa ?
12
% buried
nan
Peptide accession
Q6P9F4
Residue number A
441
Residue number B
442
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 441 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 442 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o F 637 F 670
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 637 and 670. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
9
Half-sphere exposure sum ?
83
Minimum pKa ?
11
% buried
78
Peptide accession
Q6P9F4
Residue number A
637
Residue number B
670
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 637 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 670 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o E 442 E 464
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 442 and 464. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
9
Half-sphere exposure sum ?
93
Minimum pKa ?
12
% buried
86
Peptide accession
Q6P9F4
Residue number A
442
Residue number B
464
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 442 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 464 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
2b0o H 442 H 444
A redox-regulated disulphide may form within Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 between cysteines 442 and 444. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
27
PDB code
2b0o
Structure name
crystal structure of uplc1 gap domain
Structure deposition date
2005-09-14
Thiol separation (Å)
10
Half-sphere exposure sum ?
85
Minimum pKa ?
12
% buried
71
Peptide accession
Q6P9F4
Residue number A
442
Residue number B
444
Peptide name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Ligandability
Cysteine 442 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
Cysteine 444 of Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
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