Gem-associated protein 5
Intermolecular
Cysteine 1045 and cysteine 867 L
Intramolecular
Cysteine 240 and cysteine 256 L
Cysteine 204 and cysteine 211 L
Cysteine 16 and cysteine 19
Cysteine 211 and cysteine 240 L
Cysteine 204 and cysteine 240 L
Cysteine 363 and cysteine 371
Cysteine 1463 and cysteine 1464
Cysteine 136 and cysteine 159
Cysteine 204 and cysteine 256 L
More...Cysteine 1045 and cysteine 1051
Cysteine 433 and cysteine 441 L
Cysteine 19 and cysteine 341
Cysteine 1122 and cysteine 1205
6rnq A 1045 B 867
A redox-regulated disulphide may form between two units of Gem-associated protein 5 at cysteines 1045 and 867. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
24
PDB code
6rnq
Structure name
crystal structure of the dimerization domain of gemin5 at 1
Structure deposition date
2019-05-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
91
Minimum pKa ?
12
% buried
100
Peptide A name
Gem-associated protein 5
Peptide B name
Gem-associated protein 5
Peptide A accession
Q8TEQ6
Peptide B accession
Q8TEQ6
Peptide A residue number
1045
Peptide B residue number
867
Ligandability
Cysteine 1045 of Gem-associated protein 5
Cysteine 867 of Gem-associated protein 5
5h3u B 240 B 256
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 240 and 256.
Details
Redox score ?
75
PDB code
5h3u
Structure name
sm rna bound to gemin5-wd
Structure deposition date
2016-10-27
Thiol separation (Å)
5
Half-sphere exposure sum ?
nan
Minimum pKa ?
10
% buried
26
Peptide accession
Q8TEQ6
Residue number A
240
Residue number B
256
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 240 of Gem-associated protein 5
Cysteine 256 of Gem-associated protein 5
5h1k B 204 B 211
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 204 and 211.
Details
Redox score ?
72
PDB code
5h1k
Structure name
crystal structure of wd40 repeat domains of gemin5 in complex with 13- nt u4 snrna fragment
Structure deposition date
2016-10-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
10
% buried
32
Peptide accession
Q8TEQ6
Residue number A
204
Residue number B
211
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 204 of Gem-associated protein 5
Cysteine 211 of Gem-associated protein 5
5h3t C 16 C 19
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 16 and 19.
Details
Redox score ?
70
PDB code
5h3t
Structure name
m7g cap bound to gemin5-wd
Structure deposition date
2016-10-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
87
Minimum pKa ?
7
% buried
100
Peptide accession
Q8TEQ6
Residue number A
16
Residue number B
19
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 16 of Gem-associated protein 5
Cysteine 19 of Gem-associated protein 5
5tee A 211 A 240
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 211 and 240. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
5tee
Structure name
crystal structure of gemin5 wd40 repeats in apo form
Structure deposition date
2016-09-21
Thiol separation (Å)
7
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8TEQ6
Residue number A
211
Residue number B
240
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 211 of Gem-associated protein 5
Cysteine 240 of Gem-associated protein 5
5h3t A 204 A 240
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 204 and 240. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
5h3t
Structure name
m7g cap bound to gemin5-wd
Structure deposition date
2016-10-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
10
% buried
30
Peptide accession
Q8TEQ6
Residue number A
204
Residue number B
240
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 204 of Gem-associated protein 5
Cysteine 240 of Gem-associated protein 5
5h3s B 363 B 371
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 363 and 371. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
5h3s
Structure name
apo form of gemin5-wd
Structure deposition date
2016-10-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
67
Minimum pKa ?
10
% buried
71
Peptide accession
Q8TEQ6
Residue number A
363
Residue number B
371
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 363 of Gem-associated protein 5
Cysteine 371 of Gem-associated protein 5
7xgr A 1463 A 1464
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 1463 and 1464. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
7xgr
Structure name
structure of gemin5 c-terminal region (protomer)
Structure deposition date
2022-04-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
82
Peptide accession
Q8TEQ6
Residue number A
1463
Residue number B
1464
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 1463 of Gem-associated protein 5
Cysteine 1464 of Gem-associated protein 5
5h3s B 136 B 159
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 136 and 159. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
5h3s
Structure name
apo form of gemin5-wd
Structure deposition date
2016-10-27
Thiol separation (Å)
8
Half-sphere exposure sum ?
79
Minimum pKa ?
12
% buried
93
Peptide accession
Q8TEQ6
Residue number A
136
Residue number B
159
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 136 of Gem-associated protein 5
Cysteine 159 of Gem-associated protein 5
5tef A 204 A 256
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 204 and 256. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
5tef
Structure name
crystal structure of gemin5 wd40 repeats in complex with m7gpppg
Structure deposition date
2016-09-21
Thiol separation (Å)
10
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8TEQ6
Residue number A
204
Residue number B
256
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 204 of Gem-associated protein 5
Cysteine 256 of Gem-associated protein 5
7xgr A 1045 A 1051
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 1045 and 1051. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
7xgr
Structure name
structure of gemin5 c-terminal region (protomer)
Structure deposition date
2022-04-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
30
Peptide accession
Q8TEQ6
Residue number A
1045
Residue number B
1051
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 1045 of Gem-associated protein 5
Cysteine 1051 of Gem-associated protein 5
5gxi A 433 A 441
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 433 and 441. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
5gxi
Structure name
structure of the gemin5 wd40 domain in complex with aauuuuugag
Structure deposition date
2016-09-18
Thiol separation (Å)
10
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q8TEQ6
Residue number A
433
Residue number B
441
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 433 of Gem-associated protein 5
Cysteine 441 of Gem-associated protein 5
5h3t A 19 A 341
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 19 and 341. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
29
PDB code
5h3t
Structure name
m7g cap bound to gemin5-wd
Structure deposition date
2016-10-27
Thiol separation (Å)
9
Half-sphere exposure sum ?
88
Minimum pKa ?
13
% buried
100
Peptide accession
Q8TEQ6
Residue number A
19
Residue number B
341
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 19 of Gem-associated protein 5
Cysteine 341 of Gem-associated protein 5
7xgr A 1122 A 1205
A redox-regulated disulphide may form within Gem-associated protein 5 between cysteines 1122 and 1205. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
24
PDB code
7xgr
Structure name
structure of gemin5 c-terminal region (protomer)
Structure deposition date
2022-04-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
81
Minimum pKa ?
13
% buried
98
Peptide accession
Q8TEQ6
Residue number A
1122
Residue number B
1205
Peptide name
Gem-associated protein 5
Ligandability
Cysteine 1122 of Gem-associated protein 5
Cysteine 1205 of Gem-associated protein 5
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