a tool for identifying drug-targetable redox-active disulphides

Heterogeneous nuclear ribonucleoprotein L-like

Intramolecular

Cysteine 234 and cysteine 235

A redox-regulated disulphide may form within Heterogeneous nuclear ribonucleoprotein L-like between cysteines 234 and 235.

Details

Redox score ?

71

PDB code

Structure name

crystal structure of hnrnp ll rrm2 in complex with setd2

Structure deposition date

2021-05-22

Thiol separation (Å)

4

Half-sphere exposure sum ?

64

Minimum pK_a ?

9

% buried

14

Peptide accession

Residue number A

234

Residue number B

235

Peptide name

Heterogeneous nuclear ribonucleoprotein L-like

Ligandability

Cysteine 234 of Heterogeneous nuclear ribonucleoprotein L-like

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 235 of Heterogeneous nuclear ribonucleoprotein L-like

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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