a tool for identifying drug-targetable redox-active disulphides

GTPase IMAP family member 1

Intramolecular

Cysteine 66 and cysteine 104

A redox-regulated disulphide may form within GTPase IMAP family member 1 between cysteines 66 and 104.

Details

Redox score ?

70

PDB code

Structure name

crystal structure of human gtpase imap family member 1

Structure deposition date

2011-12-20

Thiol separation (Å)

4

Half-sphere exposure sum ?

70

Minimum pK_a ?

9

% buried

92

Peptide accession

Residue number A

66

Residue number B

104

Peptide name

GTPase IMAP family member 1

Ligandability

Cysteine 66 of GTPase IMAP family member 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 104 of GTPase IMAP family member 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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