Ras association domain-containing protein 5
Intramolecular
Cysteine 132 and cysteine 135
Cysteine 146 and cysteine 149
Cysteine 149 and cysteine 165
Cysteine 146 and cysteine 165
Cysteine 132 and cysteine 157
Cysteine 135 and cysteine 157
Cysteine 132 and cysteine 153
Cysteine 146 and cysteine 153
Cysteine 153 and cysteine 157
Cysteine 149 and cysteine 153
Cysteine 135 and cysteine 153
1rfh A 132 A 135
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 132 and 135.
Details
Redox score ?
87
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
3
Half-sphere exposure sum ?
46
Minimum pKa ?
6
% buried
3
Peptide accession
O70407
Residue number A
132
Residue number B
135
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 132 of Ras association domain-containing protein 5
Cysteine 135 of Ras association domain-containing protein 5
1rfh A 146 A 149
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 146 and 149.
Details
Redox score ?
87
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
3
Half-sphere exposure sum ?
50
Minimum pKa ?
6
% buried
4
Peptide accession
O70407
Residue number A
146
Residue number B
149
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 146 of Ras association domain-containing protein 5
Cysteine 149 of Ras association domain-containing protein 5
1rfh A 149 A 165
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 149 and 165.
Details
Redox score ?
83
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
36
Minimum pKa ?
9
% buried
0
Peptide accession
O70407
Residue number A
149
Residue number B
165
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 149 of Ras association domain-containing protein 5
Cysteine 165 of Ras association domain-containing protein 5
1rfh A 146 A 165
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 146 and 165.
Details
Redox score ?
83
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
5
Half-sphere exposure sum ?
50
Minimum pKa ?
6
% buried
4
Peptide accession
O70407
Residue number A
146
Residue number B
165
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 146 of Ras association domain-containing protein 5
Cysteine 165 of Ras association domain-containing protein 5
1rfh A 132 A 157
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 132 and 157.
Details
Redox score ?
82
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
6
% buried
3
Peptide accession
O70407
Residue number A
132
Residue number B
157
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 132 of Ras association domain-containing protein 5
Cysteine 157 of Ras association domain-containing protein 5
1rfh A 135 A 157
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 135 and 157.
Details
Redox score ?
78
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
9
% buried
0
Peptide accession
O70407
Residue number A
135
Residue number B
157
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 135 of Ras association domain-containing protein 5
Cysteine 157 of Ras association domain-containing protein 5
1rfh A 132 A 153
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 132 and 153.
Details
Redox score ?
68
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
6
Half-sphere exposure sum ?
62
Minimum pKa ?
6
% buried
16
Peptide accession
O70407
Residue number A
132
Residue number B
153
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 132 of Ras association domain-containing protein 5
Cysteine 153 of Ras association domain-containing protein 5
1rfh A 146 A 153
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 146 and 153. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
67
Minimum pKa ?
6
% buried
18
Peptide accession
O70407
Residue number A
146
Residue number B
153
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 146 of Ras association domain-containing protein 5
Cysteine 153 of Ras association domain-containing protein 5
1rfh A 153 A 157
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 153 and 157. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
14
Peptide accession
O70407
Residue number A
153
Residue number B
157
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 153 of Ras association domain-containing protein 5
Cysteine 157 of Ras association domain-containing protein 5
1rfh A 149 A 153
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 149 and 153. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
53
Minimum pKa ?
9
% buried
14
Peptide accession
O70407
Residue number A
149
Residue number B
153
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 149 of Ras association domain-containing protein 5
Cysteine 153 of Ras association domain-containing protein 5
1rfh A 135 A 153
A redox-regulated disulphide may form within Ras association domain-containing protein 5 between cysteines 135 and 153. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
1rfh
Structure name
solution structure of the c1 domain of nore1, a novel ras effector
Structure deposition date
2003-11-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
54
Minimum pKa ?
10
% buried
14
Peptide accession
O70407
Residue number A
135
Residue number B
153
Peptide name
Ras association domain-containing protein 5
Ligandability
Cysteine 135 of Ras association domain-containing protein 5
Cysteine 153 of Ras association domain-containing protein 5
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