a tool for identifying drug-targetable redox-active disulphides

Protocadherin gamma C4

Intramolecular

Cysteine 99 and cysteine 105

A redox-regulated disulphide may form within Protocadherin gamma C4 between cysteines 99 and 105 (67 and 73 respectively in this structure).

Details

Redox score ?

86

PDB code

Structure name

protocadherin gammac4 ec1-4 crystal structure disrupted trans interface

Structure deposition date

2021-07-15

Thiol separation (Å)

2

Half-sphere exposure sum ?

54

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

99

Residue number B

105

Peptide name

Protocadherin gamma C4

Ligandability

Cysteine 99 of Protocadherin gamma C4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 105 of Protocadherin gamma C4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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