a tool for identifying drug-targetable redox-active disulphides

Protocadherin gamma B7

Intramolecular

Cysteine 96 and cysteine 102

A redox-regulated disulphide may form within Protocadherin gamma B7 between cysteines 96 and 102 (66 and 72 respectively in this structure).

Details

Redox score ?

87

PDB code

Structure name

protocadherin gamma b7 extracellular cadherin domains 1-4 p21 crystal form

Structure deposition date

2016-08-14

Thiol separation (Å)

2

Half-sphere exposure sum ?

49

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

96

Residue number B

102

Peptide name

Protocadherin gamma B7

Ligandability

Cysteine 96 of Protocadherin gamma B7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 102 of Protocadherin gamma B7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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