a tool for identifying drug-targetable redox-active disulphides

28S ribosomal protein S27, mitochondrial

Intramolecular

Cysteine 189 and cysteine 276

A redox-regulated disulphide may form within 28S ribosomal protein S27, mitochondrial between cysteines 189 and 276.

Details

Redox score ?

60

PDB code

Structure name

structure of human mitochondrial translation initiation factor 3 bound to the small ribosomal subunit -class i

Structure deposition date

2018-12-19

Thiol separation (Å)

6

Half-sphere exposure sum ?

59

Minimum pK_a ?

10

% buried

70

Peptide accession

Residue number A

189

Residue number B

276

Peptide name

28S ribosomal protein S27, mitochondrial

Ligandability

Cysteine 189 of 28S ribosomal protein S27, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 276 of 28S ribosomal protein S27, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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